Characterization of diethylnitrosamine-induced liver carcinogenesis in Syrian golden hamsters.

The aim of this study was to characterize hepatocarcinogenesis in diethylnitrosamine (DEN)-treated hamsters. Syrian golden hamsters (n=36) were administered DEN by hypodermic injection and addition to drinking water. Morphological analyses, including light microscopy and immunohistochemistry of α-fetal protein (AFP), were performed on liver and lung tissues.

[Studies on the chemical constituents of Rubus parvifolius].

Objective: To study the chemical constituents of Rubus parvifoliu.

Methods: The constituents were isolated by column chromatography and their structures were elucidated through spectroscopic analysis such as 1H-NMR, 13C-NMR, FT-IR, et al.

Results: Seven compounds were isolated from the roots of Rubus parvifolius L.