[Effects of airborne fine particulate matter on human respiratory symptoms and pulmonary function].

Objective: to explore effects of airborne fine particulate matter exposure on human respiratory symptoms and pulmonary function.

Methods: one hundred and seven field traffic policemen were recruited as airborne fine particulate matter high-exposure group and one hundred and one male residents as common exposure group. The individual sampler was used to measure fine particulate matter exposure levels of the two groups.

[Study of genetic damage of human B lymphocyte cell line induced by 14 nm and 280 nm carbon black particles in vitro].

Objective: To assess the genetic damage of human B lymphocyte cell line induced by 14 nm and 280 nm carbon black (CB) particles with micronucleus assay (CBMN), comet assay and hprt gene mutation test in vitro.

Methods: The genetic damage of human B lymphocyte cells exposed to 14 nm and 280 nm CB particles at the doses of 0, 128, 256, 384 and 512 microg/ml for 24 h and 48 h was detected using above three genotoxic assays. Micronucleus (MN) assay, comet assay, hprt gene mutation test were used to detect the genetic damage of human B lymphocyte cells induced by CB.

[Effects of volatile organic compounds inhalation on the inflammation biomarkers in nasal lavage fluids of decoration workers].

Objective: To study the effects of volatile organic compounds (VOCs) inhalation on the inflammation biomarkers in nasal lavage fluid (NAL), and to assess the practicability of the nasal lavage methods.

Methods: 32 volunteers joined in this study, among whom 20 Painters were chosen as exposed group, and 12 plumbers and electricians were chosen as controls. Lung function was detected, and several inflammation biomarkers (IL-4, IL-5, ECP) in nasal lavage (NAL) were determined.