[1H-NMR-based metabonomics analysis of plasma from osteoporotic rats induced by ovariectomy].

Objective: To investigate the application of metabonomics in research of osteoporosis, through detecting change of the endogenous metabolites in plasma from osteoporotic rats by ovariectomy.

Methods: Six old-months female SD rats were randomly divided into sham and OVX group. Fifth month after ovariectomy, plasma were collected from both groups, respectively.