Publications by authors named "Rong-Wei Ye"

Article Synopsis
  • Cesarean delivery on maternal request (CDMR) is linked to higher risks of childhood obesity and anemia compared to vaginal delivery (SVD), but not to pneumonia or neurobehavioral disorders.
  • The study analyzed data from 17,748 liveborn infants, focusing on 6,972 SVD and 3,626 CDMR cases, assessing health outcomes at ages 1.5 to 5 years.
  • Results suggest that women considering CDMR should be better informed about the potential health implications for their children, highlighting the need for improved obstetric care.
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Background: Cesarean delivery may reduce placental-fetal transfusion and thus increase the risk of early childhood anemia compared with vaginal delivery, but this notion has not been carefully studied in longitudinal cohorts.

Objective: The aim was to assess the association of cesarean delivery with anemia in infants and children in 2 longitudinal Chinese birth cohorts from different socioeconomic settings.

Design: Cohort 1 was recruited from 5 counties in northeastern China and cohort 2 from 21 counties or cities in southeastern China.

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Objective: To establish the method of enzyme-linked immunosorbent assay (ELISA) for measuring human IgM autoantibody to folate receptor.

Methods: Folate receptor was extracted and purified from the healthy woman placenta. The protein was coated on 96-well plates with a concentration of 5 ng/Μl.

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Article Synopsis
  • The study analyzed the effects of terminating pregnancies before 28 weeks gestation on the prevalence of neural tube defects (NTDs).
  • During 2004-2010, data from Shanxi province showed a total of 52,366 births and 485 NTD cases, revealing that terminations accounted for a significant percentage of NTDs that would otherwise go uncounted.
  • The findings suggest that existing birth defect surveillance systems need to include pregnancies terminated early to more accurately reflect the prevalence of NTDs, especially anencephaly.
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Article Synopsis
  • Cesarean section births have increased significantly in China, particularly due to maternal requests, raising concerns about its effects on children's intelligence.
  • In a study assessing IQ among 4144 preschool children, cesarean delivery on maternal request showed a slight initial increase in IQ scores compared to spontaneous vaginal delivery, but the advantage diminished after adjusting for maternal factors.
  • Ultimately, the adjusted differences in IQ were small, and assisted vaginal delivery had no significant impact on IQ scores compared to spontaneous delivery.
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Objective: In recent years, the incidence of allergic diseases in China is increasing. With serious influence on the patients' quality of life and even life-threatening, now allergic diseases have become an important public health problem in our country. This survey aimed to obtain a general epidemic outline of children's major allergic diseases, i.

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Article Synopsis
  • Maternal intake of pickled vegetables is linked to a higher risk of neural tube defects (NTDs) in offspring, according to a study in Shanxi Province, China.
  • The study included 519 cases of NTDs and 694 healthy controls, examining dietary habits shortly after delivery and using statistical models to assess risk factors.
  • Results showed that more frequent consumption of pickled vegetables significantly increased NTD risk, while higher meat and egg/milk consumption appeared to offer protective effects.
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Objective: To analyze the prevalence of asthma and asthma related symptoms among children aged 0-14 years in three Chinese cities and to obtain a crude estimation of the trend of childhood asthma prevalence in China.

Methods: A cross-sectional, population-based survey of prevalence of asthma was conducted in children aged from 0 to 14 years in 3 major cities of China (Beijing, Chongqing, and Guangzhou) with different geographic locations. All the subjects were randomly selected by a multi-stage sampling method.

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Article Synopsis
  • The study aimed to investigate how maternal hemoglobin levels during early pregnancy impact children's cognitive abilities by age 4-6 years.
  • Involving 3,609 children born during a community intervention trial, researchers measured hemoglobin concentrations during the first prenatal visit and assessed IQ using a standardized test when the children were about 68 months old.
  • The findings revealed that while children of anemic mothers had slightly higher IQ scores, these differences weren't significant after accounting for factors like the child's gender, mother's IQ, and education level, with children from the highest hemoglobin group showing a greater likelihood of poor verbal and full-scale scores.
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Objective: To analyze the influencing factors for stunting and underweight among children aged 3 - 6 years in 15 counties of Jiangsu and Zhejiang provinces so as to provide reference for enhancing growth level among preschool children.

Methods: Data was from the 183 295 records of Children Follow-up Study Project carried out by the Institute of Reproductive and Child Heath of Peking University and the records of related perinatal health care surveillance system in rural areas of 15 counties/cities of Jiangsu and Zhejiang provinces. WHO-NCHS standard was used to assess the childhood physical level of growth.

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Objective: To study the current status of spontaneous abortion of primigravid women in Jiaxing areas of Zhejiang province of China.

Methods: We analyzed the data from both perinatal healthcare surveillance program and spontaneous abortion, collected in Jiaxing areas by the Institute of Reproductive and Child Health, Peking University. The study population consisted of 14 769 primigravid women (excluding induced abortion, ectopic pregnancy and molar pregnancy as outcomes) attempting to become pregnant who registered between 1993 and 1995.

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Objective: Our purpose was to evaluate the association between hemoglobin concentration (Hb) and cognitive ability of children at 4 - 6 years of age in 21 counties/cities in China.

Methods: A total number of 7331 children born during 1993 - 1996 were randomly selected from 21 counties or cities in Hebei, Jiangsu and Zhejiang provinces. Hb concentration of children were measured followed by three tests including full-scale, verbal and performance intelligence quotient (IQ) test performed by Chinese-Wechsler Intelligence Scale for Children, one year later.

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Article Synopsis
  • The study aimed to investigate the link between pregnancy-induced hypertension (PIH) and the risks of preterm delivery (PD) and low birth weight (LBW) among 131,867 women in Zhejiang, China, from 1995 to 2000.
  • Results indicated that women with PIH had higher rates of PD (4.9%) and LBW (3.6%) compared to those without it (3.4% for PD and 1.8% for LBW), with incidence rates increasing with the severity of PIH.
  • Additionally, the timing of PIH onset influenced outcomes, showing that early onset led to higher rates of PD (8.4%) and LBW
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Objective: To understand the distribution of birth weight among premature infants and the associated social factors.

Methods: The study population consisted of 97 537 women who delivered singleton live birth of 20 to 41 gestational weeks in 4 counties/cities, Jiangsu and Zhejiang provinces, China from 1995 to 2000. Chi-square test was employed to test the difference of proportions between respective groups.

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Article Synopsis
  • The study investigates the link between pregnancy-induced hypertension (PIH) and perinatal mortality using data from over 134,000 women in Zhejiang, China, who delivered between 1995-2000.
  • The findings reveal a higher perinatal mortality rate in women with PIH compared to normotensive women, especially in cases of moderate to severe hypertension and those developing in the later stages of pregnancy.
  • After adjusting for various factors, the risk of perinatal mortality remains significantly elevated in women with moderate and severe PIH, highlighting the importance of monitoring and managing hypertension during pregnancy.
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Objective: To examine the relationship between prepregnancy body mass index (BMI) and the risk of pregnancy-induced hypertension (PIH) in Chinese population.

Methods: Data were collected in 6 counties/cities covered by Perinatal Health Care Surveillance System which was part of the Sino-American cooperative project on neural tube defects prevention established in 1992. The study population consisted of 83 159 women who attended premarital or preconception medical physical examination and delivered single live births with at least 20 gestational weeks from 1995 to 2000 in Jiaxing area.

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Objective: To assess the relationship between pre-pregnancy body mass index (BMI), weight gain during pregnancy, and the risk of neonatal asphyxia.

Methods: Data was collected in 6 countiedeities covered by Peri-natal Health Care Surveillance System which was part of a Sino-American cooperative project on neural tube defects prevention established in 1992. The study population consisted of 83,030 women who attended premarital/preconception medical physical examination program and had delivered single live birth with at least 20 gestational weeks from 1995 to 2000 in Jiaxing area, Zhejiang province.

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Objective: To examine the association between pregnancy-induced hypertension (PIH) and small-for-gestational-age babies (SGA) in a Chinese population.

Methods: Subjects were women who delivered a singleton baby (gestational weeks: equal to or greater than 28, and less than 42) in four cities or counties in Jiangsu and Zhejiang provinces, China, during the period of 1995 - 2000. A total number of 93 743 women were included.

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Article Synopsis
  • The study aimed to analyze the prevalence and yearly trends of anemia among women undergoing premarital examinations in Jiangsu and Zhejiang provinces from 1993 to 2003, using health records as data sources.
  • Over the ten-year period, 42.9% of the 193,434 women examined were found to have anemia, with rates dropping significantly from 65.5% in 1993 to 25.8% in 2003, even though certain groups like farmers, less-educated women, and older women still showed higher rates of anemia.
  • The results highlighted a downward trend in general anemia rates among these women, but emphasized that education level, body mass index,
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Objective: To describe the secular trends and epidemiological characteristics of preterm birth among singletons in 10 counties (cities) of China during 1993-2005.

Methods: We analyzed data on 542 923 women (gestational age > or =28 weeks) collected through Perinatal Healthcare Surveillance System established by the Institute of Reproductive and Child Health, Peking University. Chi-square tests were employed to test the differences in prevalence of preterm birth among different groups.

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Objective: To investigate the association between third trimester hemoglobin (Hb) concentrations and the risk of low birth weight and preterm delivery in a Chinese population.

Methods: Subjects were women who delivered in four cities/counties in Jiangsu and Zhejiang provinces, China, during the period of 1995 - 2000. Incidence of low birth weight and preterm delivery was calculated and compared among groups of women with different levels of Hb during the third trimester.

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Objective: To understand the current status and its changing patterns of perinatal health care in some southern and northern areas of China from 1994 to 2000.

Methods: Data was collected in 13 counties/cities covered by Perinatal Health Care Surveillance System which was part of the Sino-American cooperative project on neural tube defects prevention, established in 1992. The study population consisted of 368 589 women who delivered single live births of at least 20 gestational weeks from 1994 through 2000.

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Article Synopsis
  • The study evaluated how access to prenatal care varies among women of different educational levels in select regions of China.
  • Data was collected from over 100,000 women who gave birth in 1994 and 2000, analyzing factors like systematic management rates and changes in equity using statistical methods.
  • Results showed an increase in prenatal care utilization rates over time, but growing inequities, particularly in northern areas, suggesting a need for improved access and focus on vulnerable populations.
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