[Evaluation of the preclinical teaching effects of digital virtual simulation system in veneer tooth preparation].

Purpose: To evaluate the preclinical teaching effects of digital virtual simulation system applied in window-type veneer tooth preparation of undergraduate dental students.

Methods: In the early clinical exposure of five-year undergraduate students from School of Stomatology, Fudan University, Simodont virtual simulation system and conventional phantom-simulator system were alternatively used in the preclinical teaching of veneer tooth preparation. First, after theoretical training and tests of veneer tooth preparation, twenty-three students were randomly divided into two groups.

Dezocine as a potent analgesic: overview of its pharmacological characterization.

Dezocine, a synthetic opioid, introduced in 1970s as an analgesic, was redeveloped for relieving moderate to severe pain by Yangtze River Pharmaceutical Group in China in 2009. To date, dezocine occupies 45% of China's opioid analgesic market. Along with dezocine being a dominated painkiller, a certain amount of research was conducted to elucidate dezocine's action.

Uhrf1 regulates H3K9me2 modification of mTOR to inhibit the effect of autophagy in myocardial ischemia-reperfusion injury.

The regulation of mTOR and the dimethylation of histone H3 on lysine 9 (H3K9me2) H3K9me2 by Uhrf1 and the mechanism of autophagy regulation in myocardial ischemia-reperfusion injury (MIRI) were studied and . An I/R injury model was established using the primary mouse cardiomyocytes treated with HO. Subsequent analysis by qRT-PCR, western blot, and immunofluorescence indicated that overexpression of Uhrf1 significantly inhibited apoptosis of the HO-treated cardiomyocytes, reduced expression of apoptosis factors caspase-3 and Bax, and increased expression of apoptosis inhibitory factor Bcl-2.

[Changes of abutment alveolar height after Stern ERA attachment restoration].

Purpose: To observe the alveolar height changes of the distal abutments in Kennedy II dentition defect restored with Stern ERA attachment.

Methods: Twenty-one Kennedy II dentition defect patients restored with Stern ERA attachment were observed at the day of restoration and 1 month, 3 months and 6 months after restoration. Digital panoramic radiographs were taken to measure the vertical distances from the distal and the mesial alveolar bone crest to the apical point in the distal abutments and were used to observe and compare the alveolar height changes of the distal abutments.

[Cytotoxicity of three kinds of temporary crown and bridge materials on mouse fibroblasts in vitro].

Purpose: This study was to investigate the cytotoxicity in vitro of three kinds of common temporary crown and bridge materials, i.e.,self-curing resin, heat-curing resin, and DMG-TEMP bi-acrylic composite.