Publications by authors named "Rong-Ping Huang"
Article Synopsis
- - Alcohol liver disease (ALD) is a serious health issue caused by liver damage from alcohol; this study investigates the hepatoprotective effects of tamarind shell extract (TSE) using chick embryos and other models exposed to ethanol.
- - TSE treatment in chick embryos significantly improved liver function and reversed damage by reducing oxidative stress markers, restoring important antioxidant enzymes and glutathione levels, and promoting mitochondrial health.
- - The study found that TSE activates key proteins like NRF2 and HO-1, which help protect against ethanol-induced oxidative stress, suggesting its potential as a treatment for ALD.
Neural tube defect (NTD) is the most common and severe embryopathy causing embryonic malformation and even death associated with gestational diabetes mellitus (GDM). Leu-Pro-Phe (LPF) is an antioxidative tripeptide isolated from hydrolysates of corn protein. However, the biological activity of LPF and remains unclear.
View Article and Find Full Text PDFExcessive reactive oxygen species (ROS) accumulation is involved in the pathogenesis of liver fibrosis and damage, specifically in the developing embryo that is extremely sensitive to oxidative stress. Herein, a liver injury model in chick embryo was established by using 2,2-azobis (2-amidinopropane) dihydrochloride (AAPH), which was used to investigate the effect of cyclo(-Phe-Phe) (CPP), a natural dipeptide found in foods and beverages. The results showed that CPP significantly alleviated AAPH-induced liver pathological damage, hepatic dysfunction and inhibited the excessive production of ROS in both chick embryo liver and HepG2 cells.
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