Publications by authors named "Rong-Lin Yan"
Acute pancreatitis (AP) is a common inflammatory disease mediated by damage to acinar cells and subsequent pancreatic inflammation with infiltration of leukocytes. The neuronal guidance protein, netrin-1, has been shown to control leukocyte trafficking and modulate inflammatory responses in several inflammation-based diseases. The present study was aimed toward investigating the effects of netrin-1 in an in vivo model of AP in mice.
View Article and Find Full Text PDFBackground: The number of citations of an article in scientific journals reflects its impact on a biomedical specialty and its recognition in the scientific community. In this study, we identified and analyzed the 100 most highly cited articles published between 1971 and 2011 in journals pertaining to plastic and reconstructive surgery research.
Methods: We selected 6 high-impact journals for literature search in the database of the Science Citation Index (1971 to 2011).
Article Synopsis
- This study explores the use of nano-silver particles combined with porcine-derived small intestinal submucosa (PSIS) to improve antibacterial properties in repairing infected abdominal wounds.
- The research demonstrates that NS-PSIS shows significant antibacterial effectiveness against common pathogens and reduces surgical site infection rates in rat models, compared to traditional materials.
- Importantly, NS-PSIS maintains the original tissue properties and demonstrates no adverse effects, making it a promising option for improving surgical repair outcomes.
Hydrogen-rich saline ameliorates the severity of l-arginine-induced acute pancreatitis in rats.
Biochem Biophys Res Commun
March 2010
Molecular hydrogen, which reacts with the hydroxyl radical, has been considered as a novel antioxidant. Here, we evaluated the protective effects of hydrogen-rich saline on the l-arginine (l-Arg)-induced acute pancreatitis (AP). AP was induced in Sprague-Dawley rats by giving two intraperitoneal injections of l-Arg, each at concentrations of 250mg/100g body weight, with an interval of 1h.
View Article and Find Full Text PDFBackground: Hydrogen has been considered as a novel antioxidant that prevents injuries resulted from ischemia-reperfusion (I/R) injury in various tissues. The study was designed to determine the effect of hydrogen-rich saline on the smooth muscle contractile response to KCl, and on epithelial proliferation and apoptosis of intestine subjected to I/R.
Methods: Intestinal I/R injury was induced in Sprague-Dawley rats using bulldog clamps in superior mesenteric artery by 45 min ischemia followed by 1 h reperfusion.