Multifunctional ZnO-Loaded Colloidosomes with Multiple Synergies as a UV Filter.

ZnO nanoparticles with high safety and stability are often used as active ingredients in sunscreens to protect the skin from ultraviolet rays. However, ZnO nanoparticles are easy to agglomerate, which will significantly affect the ultraviolet absorption and bacteriostatic properties, and the reactive oxygen species induced by the photocatalytic activity may result in irreversible secondary damage to the skin. Herein, the ZnO nanoparticles are dispersed uniformly on the surface of latex particles, and these composite particles are used as shell materials to construct self-assembled colloidosomes by high-gravity technology, which can improve the application properties with synergistic enrichment of the hollow structure.

Asymmetric Assembly in Microdroplets: Efficient Construction of MOF Micromotors for Anti-Gravity Diffusion.

Janus-micromotors, as efficient self-propelled materials, have garnered considerable attention for their potential applications in non-agitated liquids. However, the design of micromotors is still challenging and with limited approaches, especially concerning speed and mobility in complex environments. Herein, a two-step spray-drying approach encompassing symmetrical assembly and asymmetrical assembly is introduced to fabricate the metal-organic framework (MOF) Janus-micromotors with hierarchical pores.

Efficient Construction of pH-Stimuli-Responsive Colloidosomes with High Encapsulation Efficiency.

Intelligent responsive colloidosomes have attracted increasing attention for their potential to enhance the efficacy and decrease the side effects of drugs in biomedical applications. However, a low encapsulation efficiency and complicated preparation method greatly limit their development. Herein, we report an efficient approach for the construction of pH-stimuli-responsive colloidosomes with high encapsulation efficiency by a high-gravity technology.

Greatly Intensified Guest Exchange Strategy for Highly-Efficient Activation of Metal-Organic Frameworks.

The preservation and accessibility of pores are prerequisites to the application of metal-organic frameworks (MOFs). Activation is a key step to eliciting rich features of pores, but it needs a repeated solvent-exchange process which is tedious and time/cost-consuming. Herein, a facile strategy for highly-efficient activation of MOFs utilizing rotating packed bed is proposed.

Three-Fluid Nozzle Spray Drying Strategy for Efficient Fabrication of Functional Colloidosomes.

Colloidosomes as Pickering emulsion microcapsules are expected to serve various applications, including encapsulation of drugs and loading of functional materials. Normally, when using colloidosomes for drug encapsulation, the latex particles as shell materials need to be mixed with drugs before the assembly process. However, this procedure may cause aggregation of latex particles, thereby resulting in disordered assembled shells or a low loading efficiency.

Association between serum uric acid level and endothelial dysfunction in elderly individuals with untreated mild hypertension.

Background: Endothelial dysfunction is the initial stage in atherosclerotic formation and progression and is associated with high serum uric acid (SUA) level. We hypothesized that reactive hyperemia index (RHI), which reflects endothelial function, is associated with SUA levels in elderly individuals with untreated mild hypertension.

Methods: We recruited 123 patients ≥ 60 years with untreated mild hypertension.

Associations between human aldosterone synthase CYP11B2 (-344T/C) gene polymorphism and antihypertensive response to valsartan in Chinese patients with essential hypertension.

Aldosterone synthase is a mitochondrial enzyme that catalyzes the conversion of 11-deoxycorticosterone to the potent mineralocorticoid aldosterone. The gene encoding aldosterone synthase, CYP11B2, is associated with essential hypertension. But if the genetic variations in aldosterone synthesis could influence the antihypertensive response to Valsartan is not clear.

Interleukin-6, but not soluble adhesion molecules, predicts a subsequent mortality from cardiovascular disease in patients with acute ST-segment elevation myocardial infarction.

Inflammatory responses are an important element in the atherosclerotic process. Therefore, inflammatory markers can potentially serve as predictors of cardiovascular risk. However, the existing data are limited and controversial.

Association between two common polymorphisms of PPARgamma gene and metabolic syndrome families in a Chinese population.

Background And Aims: We investigated the association between the two common polymorphisms, C1431T and Pro12Ala of PPARgamma gene, and metabolic syndrome (MS) in a Chinese population.

Methods: We included 423 subjects with MS and families without MS. Subjects were divided into three groups: MS probands and first- and second-degree relatives of probands, spouses and controls.

[Investigation and analysis of the prevalence and risk factors for impaired fasting glucose in outpatients with essential hypertension].

Objective: To evaluate the prevalence of impaired fasting glucose (IFG) in outpatients with essential hypertension and the influencing factors.

Methods: 1026 essential hypertensive outpatients aged 15 - 87 years [531 males and 495 females, mean age (51.6 +/- 12.

[A cohort study on the correlation between birth weight, simple obesity, blood lipids, blood glucose and blood pressure from childhood to adolescence].

Objective: To determine the correlation between birth weight and simple obesity, blood lipids, blood glucose and blood pressure from childhood to adolescence.

Methods: A vertical sectional survey on 193 children aged 7 - 11 years was performed in 1996. A questionnaire consisting of items on environmental factors and lifestyle, physical examination and biochemical assessment was conducted at baseline and the 9th year of follow-up.

[A cohort study on the relationship between body mass index and blood pressure, blood lipid, blood glucose, left ventricular structure and function in adolescents during transition period].

Objective: To investigate the relationship between body mass index(BMI) and blood pressure, blood lipid level, blood glucose, left ventricular structure and function in adolescents during transition period.

Methods: A vertical sectional survey on 193 pupils aged 7-11 years in primary school in 1996 was performed. 9 years later, the same research subjects aged 16-20 years were studied again in 2005.

[Effect of E-selectin A561C (S128R) polymorphism on blood pressure].

Objective: To investigate the effect of E-selectin A561C (S128R) polymorphism on blood pressure.

Methods: 347 essential hypertensive patients (male 163 and female 184, age 46.08 +/- 12.

[A study on the risk factors of cardiovascular between hypertensive patients and normal subjects in the same family].

Objective: Through studying the difference between the hypertensive patients and those with normal blood pressure who all from the same hypertensive pedigree, we tried to find the factors which would decrease the risk of hypertension.

Methods: Hypertensive patients, when coming to the cardiovascular clinic of Xuan Wu Hospital from 2003 to 2004, were defined as the members of the hypertensive pedigrees through inquiry. 84 families including 368 persons, with 192 syblings were involved.

[Relationship between the patients' knowledge on hypertension prevention and control and the rate on blood pressure control].

Objective: To study the relationship between blood pressure control status and patients' knowledge on hypertension prevention and control among hypertensive patients.

Methods: A total of 726 hypertensives were selected from four community health service centers (2 urban and 2 rural) in Beijing. All subjects were investigated by questionnaires and their blood pressures were measured at the same time.