Publications by authors named "Rong-Jiong Zheng"
Article Synopsis
- Acute-on-chronic liver disease (AoCLD) is a major cause of hospitalization in hepatology, prompting a study to better understand its characteristics for diagnosis and prognosis.
- A total of 3,375 patients were analyzed, highlighting that liver cirrhosis acute decompensation (LC-AD) is the most common type, with hepatitis B virus (HBV) being the leading cause of chronic liver disease.
- The study revealed high mortality rates associated with AoCLD subtypes, emphasizing that bacterial infections are significant precipitating factors and that timely medical intervention is crucial for improving patient outcomes.
Objectives: To investigate the relationship between systemic inflammatory response and short-term mortality in patients with non-cirrhotic chronic severe hepatitis (CSH) by using several indicators of inflammation including neutrophil-to-lymphocyte ratio (NLR), neutrophil (NEU), white blood cell (WBC), platelet-to lymphocyte ratio (PLR), and monocyte-to-lymphocyte ratio (MLR).
Methods: Data were collected from two prospectively enrolled CATCH-LIFE noncirrhotic cohorts. Cox regression analysis was used to investigate the association between systemic inflammatory biomarkers and 90-day liver transplant (LT)-free mortality.