PoIL8-L, a teleost interleukin-8 like, enhances leukocyte cellular vitality and host defense against bacterial infections in Japanese flounder (Paralichthys olivaceus).

Interleukin-8 (IL-8), a CXC chemokine, exerts pivotal effect on cell migration, inflammatory response, and immune regulation. In this study, we examined the immunological characteristics of an IL-8 like homologue (PoIL8-L) in Japanese flounder (Paralichthys olivaceus). PoIL8-L contains a conserved chemokine CXC domain and 105 amino acid residues.

Comparative Genomic Analysis of Asian Cultivated Rice and Its Wild Progenitor () Has Revealed Evolutionary Innovation of the Pentatricopeptide Repeat Gene Family through Gene Duplication.

The pentatricopeptide repeat () gene family is one of the largest gene families in land plants. However, current knowledge about the evolution of the gene family remains largely limited. In this study, we performed a comparative genomic analysis of the gene family in and its wild progenitor, , and outlined a comprehensive landscape of gene duplications.

[Determinants of Drinking Relapse after Treatments in Patients with Alcohol Dependence in Sichuan Province].

Objective: To identify factors that influent drinking relapse after treatments in patients with alcohol dependence in Sichuan province.

Methods: Data were collected in 10 cities of Sichuan province from September 2014 to June 2015,involving 599 patients who received treatments for alcohol dependence. A questionnaire survey was administered on these patients one year after discharge through face to face interviews,collecting data in relation to their demographic characteristics,drinking over the past year,smoking,mood and level of stress.

Pharmacokinetics and bioequivalence evaluation of two different atorvastatin calcium 10-mg tablets: A single-dose, randomized-sequence, open-label, two-period crossover study in healthy fasted Chinese adult males.

Background: Atorvastatin calcium is a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor indicated for the prevention of cardiovascular disease and for the treatment of dyslipidemia. Information on the pharmacokinetics of atorvastatin in a Chinese population is lacking, and regulatory requirements necessitate a bioequivalence study for the marketing of a generic product in China.

Objective: The aim of the present study was to assess the pharmacokinetics and bioequivalence of a test and branded reference formulation of atorvastatin calcium 10-mg tablets in healthy fasted Chinese male volunteers.