Laryngeal morphologic changes and epidemiology in patients with inhalation injury: a retrospective study.

Background And Objectives: Laryngeal morphologic changes are important in risk assessment of upper airway obstruction (UAO) after inhalation injury. This retrospective study evaluates the clinical application of laryngeal burn classification system.

Materials And Methods: Clinical data from January 1999 to June 2013 were analyzed retrospectively.

Pathological changes of the three clinical types of laryngeal burns based on a canine model.

Objective: The study was designed to examine pathological changes of inhalational laryngeal burns of three clinical types: congestive, oedematous and obstructive.

Methods: A total of 18 healthy, male, adult Beagle dogs were randomly assigned to inhale hot dry air at room temperature (group C), 80°C (Group 1), 160°C (Group 2) or 320°C (Group 3) for 20min to induce inhalation injury. Each larynx was evaluated and scored based on the 'clinical scoring and typing system of laryngeal burns at early stage'.

Epidemiology of 1974 burn patients at a major burn center in Beijing: a nine-year study.

To date, little epidemiological data are available on burns in China. This study describes the characteristics of burn patients admitted to a major burn center in Beijing to show trends in admission and outcomes in burned patients to share information about the current state of care for burned patients in our burn center. A retrospective study on 1974 burn patients admitted to Jishuitan Hospital in Beijing was conducted during the 9-year period from 2000 to 2008, and data were collected on age, gender, TBSA, etiology, length of hospital stay, mortality, and inhalation injury.

Temperature distribution in the upper airway after inhalation injury.

Objective: The aim of the study was to establish an animal model of laryngeal burn and to investigate the temperature distribution of heated air in the upper airway.

Methods: The animal model was established by inhalation of dry heated air at 80, 160 and 320 °C in 18 healthy, male, adult hybrid dogs. Time for inducing injury was set at 20 min.

[Quantification of type I and III collagen content in normal human skin in different age groups].

Objective: To quantify the content of type I, III collagen and their ratio in normal human skin of different age, and to explore the regulation of changes.

Methods: The normal human skin specimens were obtained from 6 spontaneously aborted fetus and 56 burn patients of different ages, including infants (newborn -3 years), pre-school group ( > 3, < or =7 years), adolescent group ( >7, < or = 18 years), youth and middle age group ( > 18, < or = 50 years), and elderly group ( > 50 years), were studied. The total collagen content were determined by hydroxyproline method.