Publications by authors named "Rong J"

Introduction:Few studies have evaluated different patterns of in-stent restenosis by optical coherence tomography (OCT). This study aims to identify in vivo predictors for focal restenosis in patients with in-stent restenosis (ISR). Methods: The study recruited patients with ISR who underwent OCT examination in the Cardiology Department of the Affiliated Hospital of Zunyi Medical University from October 2018 to December 2022.

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The aim of this study was to investigate the biomarkers of salivary and fecal microbiota in Colorectal cancer (CRC). Initially, the study scrutinized the microbial community composition disparities among groups. Utilizing Lasso analysis, it sifted through operational taxonomic units (OTUs) to pinpoint distinctive features.

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Article Synopsis
  • This study examines the prevalence of co-infections with Burkholderia cepacia complex (Bcc) in patients with respiratory infections like COVID-19 and H7N9, highlighting a lack of previous research on this topic.
  • A total of 49 Bcc isolates were analyzed from patients, revealing that those infected with COVID-19 had a higher rate of multidrug resistance and a shorter median lethal time compared to those with H7N9.
  • The findings suggest that COVID-19-Bcc may have evolved from H7N9-Bcc, demonstrating increased virulence and antibiotic resistance in the context of respiratory infections.
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Background: Smartphone apps can be used to monitor chronic conditions and offer opportunities for self-assessment conveniently at home. However, few digital studies include older adults.

Objective: We aim to describe a new electronic cohort of older adults embedded in the Framingham Heart Study including baseline smartphone survey return rates and survey completion rates by smartphone type (iPhone [Apple Inc] and Android [Google LLC] users).

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Nanomaterials, heralded as the "new materials of the 21st century" for their remarkable physical and chemical properties and broad application potential, have attracted substantial attention in recent years. Among these materials, which challenge traditional physical boundaries, nanodiamonds (NDs) are widely applied across diverse industries due to their exceptional surface multifunctionality and chemical stability. Nevertheless, atomic-level manipulation of NDs presents considerable challenges, which require detailed structural analysis to thoroughly elucidate their properties.

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Objectives: This study aimed to evaluate and compare the efficacy and safety of different acupuncture and moxibustion techniques as adjunctive therapy in addressing Postoperative gastrointestinal dysfunction (PGD) associated with gastric cancer (GC).

Methods: Eight medical databases were comprehensively searched for relevant randomized controlled trials (RCTs) as of October 2024. A network meta-analysis (NMA) was performed using frequency models, combining all available direct and indirect evidence from RCTs.

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The cultivated Zizania latifolia, an aquatic vegetable prevalent in the Yangtze River Basin, represents a unique plant-fungus complex whose domestication is associated with host-parasite co-evolution. In this study, we present a high-quality, chromosome-scale genome assembly of cultivated Z. latifolia.

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Reducing carbon dioxide (CO) levels in the atmosphere is crucial for combating global warming. One effective strategy involves using porous materials for the combined processes of CO capture and catalytic conversion. In this study, we developed composite aerogel materials using cellulose nanocrystals (CNCs) as templates, doped with cerium oxide, to enhance CO capture and conversion.

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Breast cancer is the second leading cause of cancer deaths among women. Multiple microRNAs (miRNAs) have been reported to be associated with breast cancer progression or metastasis. The purpose of the current study was to identify plasma extracellular miRNAs associated with incident breast cancer.

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  • Histomonosis is a protozoan disease that affects poultry and causes significant economic losses in China, prompting the development of an attenuated vaccine based on a less virulent strain.
  • Four experiments were conducted to test the viability of the attenuated strain, including comparing different infection routes, doses, and immunization schedules to determine the most effective vaccination strategy.
  • Results indicated that the intracloacal route was more effective than oral administration, particularly with a vaccination dose of 2 × 10 on day 14, which led to better weight gain and fewer health issues in vaccinated chickens.
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Aims: To assess responses to lifestyle interventions (LIs) among individuals with distinct pre-diabetes phenotypes (isolated impaired fasting glucose [i-IFG], isolated impaired glucose tolerance [i-IGT], and combined IFG + IGT) for reducing diabetes incidence, reversing pre-diabetes, and improving glycemic control and insulin sensitivity.

Methods: PubMed, Embase, Cochrane Library, and Web of Science were searched until December 6th, 2023. We included randomized controlled trials examining responses to LIs (including diet and/or physical activity) among adults with i-IFG, i-IGT, and IFG + IGT.

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In this study, a retrospective analysis was conducted to investigate the associations between systemic inflammation markers and persistent atrial fibrillation (pAF), intending to identify potential biomarkers for early detection of pAF.In the analysis, a total of 207 patients were included, with 109 in the pAF group and 98 in the non-pAF group. The associations between three systemic inflammation markers were investigated, namely, the systemic immune inflammation index (SII), system inflammation response index (SIRI), and aggregate index of systemic inflammation (AISI), and pAF.

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Background: Tissue regenerative capacity following evisceration, potentially influenced by environmental contaminants and intestinal microflora, is essential for the financial success of farming. However, the morphological structure, gut microbiome composition, and genes expression pattern of the regenerated gut after exposure to high levels of TBBPA remain poorly unclear.

Methods: In this research, the effect of TBBPA exposure on tissue regeneration in was investigated through a comprehensive multi-omics approach.

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Glycogen synthase kinase 3 (GSK3) is a multifunctional serine/threonine kinase family that regulates diverse biological processes including glucose metabolism, insulin activity and energy homeostasis. Dysregulation of GSK3 is implicated in the development of several diseases such as type 2 diabetes mellitus, Alzheimer's disease (AD), and various cancer types. In this study, we report the synthesis and evaluation of a novel positron emission tomography (PET) ligand compound 28 (codenamed [F]GSK3-2209).

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Metabotropic glutamate receptor 7 (mGlu) is a G protein-coupled receptor that is preferentially found in the active zone of neurotransmitter release in the central nervous system (CNS). mGlu plays a vital role in memory, learning, and neuronal development, rendering it a potential target for treating epilepsy, depression, and anxiety. The development of noninvasive imaging ligands targeting mGlu could help elucidate the functional significance of mGlu and accelerate drug discovery for neurological and psychiatric disorders.

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Article Synopsis
  • - The study investigates the role of collagen type VIII alpha-1 chain (COL8A1) in gliomas, revealing that its overexpression in glioma tissues is linked to worse patient outcomes.
  • - Reducing COL8A1 levels in glioma cells through shRNA or knockout decreased cell survival, growth, and movement, while also triggering cell death.
  • - In animal models, a lack of COL8A1 inhibited tumor growth and affected key signaling pathways related to cancer progression, suggesting that COL8A1 encourages glioma cell proliferation.
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  • Mucosal healing is a key goal in treating ulcerative colitis (UC), but the roles of amino acids (AAs) and gut microbiota in this process are not fully understood.
  • A study involving 15 UC patients assessed changes in serum and fecal AA concentrations and gut microbiota composition before and after mucosal healing to identify potential biomarkers and improve dietary therapy.
  • Results showed significant changes in AA levels, with glutamic acid, leucine, lysine, methionine, and threonine emerging as strong predictors for mucosal healing, achieving a predictive accuracy of 0.96 when combined.
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Frequency-modulated continuous-wave (FMCW) narrow linewidth lasers have served as the cornerstone behind applications such as autonomous driving, wearable technology, virtual reality, and remote sensing mapping. Strongly coherent lasers are typically used for these studies, with a clear demand for linear fast response and wide frequency tuning range. In this paper, profiting from the ultrahigh-quality factor of the crystalline whispering-gallery-mode resonator, by using a self-injection locking mechanism to suppress spontaneous emission noise and improve coherence, sub-kHz linewidth at 450 nm is obtained.

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Reducing the size of catalysts and tuning their electronic structure and interfacial properties are key to enhancing catalytic performance. Herein, a series of quantum-sized Co-based nanodot composites, including CoO/C, CoS/C, CoN/C, and CoP/C, were synthesized using chemical vapor deposition (CVD) methods. By means of experimental measurement and theoretical calculation, CoP/C exhibited more robust electrochemical response than other Co-based compounds in electrochemical oxidation of NH (HzOR) and hydrogen evolution reaction (HER).

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Background: Previous studies found it difficult to differentiate hepatoid adenocarcinoma of the stomach (HAS) from conventional gastric adenocarcinoma (CGA). We aimed to assess the efficacy of a computed tomography (CT)-based radiomics nomogram in identifying HAS.

Methods: Portal phase CT images were collected from 59 patients with HAS and 122 patients with CGA.

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A novel poly(2-hydroxyethyl methacrylate-co-methacrylated hyaluronan-β-cyclodextrin) [p(HEMA-co-mHA-β-CD)] hydrogel was developed as a potential contact lens for ophthalmic disease. The hydrogel was synthesized from the copolymerization of 2-hydroxyethyl methacrylate (HEMA) monomer and mHA-β-CD as a hydrophilic macromolecular crosslinker. By adjusting the methacrylate substitution degree in hyaluronan (20-29 %) and the mHA-β-CD content (5-11 %), transparent p(HEMA-co-mHA-β-CD) hydrogels were achieved.

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Phosphodiesterases (PDEs) constitute a superfamily of phosphohydrolytic enzymes that regulate intracellular second messenger signaling by hydrolyzing cyclic adenosine monophosphate and cyclic guanosine monophosphate. Among the 11 subfamilies of PDEs, phosphodiesterase 1 (PDE1) stands out due to its broad implications in central and peripheral pathologies. There are three subtypes of PDE1: PDE1A, PDE1B, and PDE1C.

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Background: Clinically important lineages in Klebsiella, especially those expressing multi-drug resistance (MDR), pose severe threats to public health worldwide. They arose from the co-evolution of the vertically inherited core genome and horizontal gene transfers by plasmids, which has not been systematically explored.

Methods: We designed KleTy, which consists of dedicated typing schemes for both the core genome and plasmids in Klebsiella.

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Approximately 200 critically ill infants and children in New Zealand are in high-dependency care, many suspected of having genetic conditions, requiring scalable genomic testing. We adopted an acute care genomics protocol from an accredited laboratory and established a clinical pipeline using Oxford Nanopore Technologies PromethION 2 solo system and Fabric GEM™ software. Benchmarking of the pipeline was performed using Global Alliance for Genomics and Health benchmarking tools and Genome in a Bottle samples (HG002-HG007).

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