Health-Promoting Lifestyle and Its Predictors in Renal Transplant Recipients in Hunan, China: A Cross-Sectional Study.

Background: Kidney transplantation is a critical treatment for end-stage renal disease (ESRD), with health-promoting lifestyle (HPL) significantly impacting patient outcomes. HPL involves behaviors like regular exercise, balanced nutrition, stress management, and habit modification. However, few studies have analyzed the HPL of renal transplant recipients, addressing a significant gap in current research.

[Removal of Cr(Ⅵ) via a Nickel Ferrite@Activated Carbon Composite Under Batch Experiments: Study of Characterization, Performance, and Mechanism].

A magnetic activated carbon adsorbent named NiFeO@AC was synthesized by modifying activated carbon with NiFeO and used for the adsorption of Cr(Ⅵ) ions from waste water. The influencing factors, adsorption kinetics, and adsorption isotherms of Cr(Ⅵ) adsorption by the adsorbent were investigated. The results showed that the removal rate of Cr(Ⅵ) adsorption by NiFeO@AC reached 96.

Association between increased serum interleukin-8 levels and improved cognition in major depressive patients with SSRIs.

Background: The effect of neuroinflammatory cytokines on cognitive deficits in patients with major depressive disorder (MDD) can be altered by selective serotonin reuptake inhibitors (SSRIs). This study aimed to examine serum interleukin-8 (IL-8) levels, cognitive function, and their associations in MDD patients with SSRIs.

Methods: Thirty SSRI-treated MDD patients and 101 healthy controls were recruited for this study.

[Temporal and Spatial Distribution, Utilization Status, and Carbon Emission Reduction Potential of Straw Resources in China].

Based on the crop yield data of China and each region from 1981 to 2020 (excluding data from Hong Kong, Macao, and Taiwan), by using the grain-straw ratio method, this study estimated the total amount of crop straw and collectable amount of crops, including corn, rice, wheat, other cereals, cotton, rapeseeds, peanuts, beans, tubers, sesame, fiber crops, sugarcane, and beetroots, and the spatial and temporal distribution characteristics of resource density and per capita resources of crop straw were analyzed. This study analyzed the current utilization mode, development, and change of crop straw in China. Finally, we used the life circle assessment (LCA) method to estimate the carbon emission reduction potential of biochar prepared from crop straw.

Comparisons of Serum Interleukin-8 Levels in Major Depressive Patients With Drug-Free Versus SSRIs Versus Healthy Controls.

Objective: The interleukin-8 (IL-8) has been reported to play an important role in depression, which might be modulated by the selective serotonin reuptake inhibitors (SSRIs). Thus, the aim of this study was to investigate serum IL-8 levels, depressive symptom, and their associations in drug-free MDD patients, MDD patients with SSRIs, and healthy controls (HCs).

Methods: Fifty-seven drug-free MDD patients (male/female = 35/22, mean age: 39.

ATP catabolism and bacterial succession in postmortem tissues of mud crab (Scylla paramamosain) and their roles in freshness.

The seafood microbiome is highly diverse and plays an essential role in the spoilage of seafood. Nevertheless, how such a diverse microbiome influences freshness of mud crab (Scylla paramamosain) remains unclear. Here we investigated the postmortem ATP catabolism and succession of the bacterial community in the hepatopancreas and muscle of S.

Effect of silibinin on ethanol- or acetaldehyde-induced damge of mouse primary hepatocytes in vitro.

Silibinin, one of the flavonoids isolated from milk thistle seeds of Silybum marianum, has hepatoprotective properties against toxins in clinical. However, the detailed mechanisms have remained unclear. This study investigates the underlying mechanism of silibinin in the protection against ethanol- or acetaldehyde-induced damage of neonatal mouse primary hepatocytes in vitro.

Suppression of KIF22 Inhibits Cell Proliferation and Xenograft Tumor Growth in Tongue Squamous Cell Carcinoma.

Background: Oral carcinoma is the sixth most common cancer and is a serious public health problem, and tongue squamous cell carcinoma (TSCC) is the most common type of oral carcinoma. Kinesin family member 22 (KIF22), also called as kinesin-like DNA binding protein (KID), is a microtubule-based motor protein and binds to both microtubules and chromosomes, transporting organelles, protein, and mRNA. This research aimed at investigating the prognostic significance of KIF22 in TSCC.

Large branch and leaf hydraulic safety margins in subtropical evergreen broadleaved forest.

As a global biodiversity hotspot, the subtropical evergreen broadleaved forest (SEBF) in southern China is strongly influenced by the humid monsoon climate, with distinct hot-wet and cool-dry seasons. However, the hydraulic strategies of this forest are not well understood. Branch and leaf hydraulic safety margins (HSMbranch and HSMleaf, respectively), as well as seasonal changes in predawn and midday leaf water potential (Ψpd and Ψmd), stomatal conductance (Gs), leaf to sapwood area ratio (AL/AS) and turgor loss point (Ψtlp), were examined for woody species in a mature SEBF.

[Application Potential and Assessment of Metallurgical Contaminated Soil After Remediation in Tongguan of Shaanxi].

There has been a growing interest in soil replacement and in-situ stabilization techniques in recent years. Many techniques in the remediation of contaminated soils have been proven to be effective methods. In this study, lime and calcium phosphate were added to immobilize the heavy metals in contaminated soils.

[Effect of Ca-bentonite on Cu and Zn Forms in Compost and Soil, and Their Absorption by Chinese Cabbage].

Aerobic composting was conducted to evaluate the effects of the different ratios (0%, 2.5%, 5%, 7.5%, and 10%) of Ca-bentonite (CB) on the speciation of Cu and Zn during pig manure composting, while pot experiment was performed to investigate the role of CB-added compost on the bio-availability of Cu and Zn to Chinese cabbage and its biomass.

[Effects of Bentonite Amendment on Detoxification, Heavy Metal Passivation and Estrone Elimination of Sewage Sludge Compost].

Sewage sludge was amended with calcium-based bentonite with addition of no more than 10% in dry weight during the 52-day aerobic composting process, the variations of temperature, pH, organic carbon, EC, total nitrogen, nitrate(NH-N) and ammonium(NO-N) were investigated, as well as the compost detoxification(germination test), heavy metals(Zn, Cu, Pb, Cd) passivation and estrone(E1) elimination. The results showed that the amendment facilitated the thermophilic phase, promoted the compost heat inactivation and brought the organic carbon mineral up to more than 15.27% -19.

Leaf turgor loss point is correlated with drought tolerance and leaf carbon economics traits.

Leaf turgor loss point (πtlp) indicates the capacity of a plant to maintain cell turgor pressure during dehydration, which has been proven to be strongly predictive of the plant response to drought. In this study, we compiled a data set of πtlp for 1752 woody plant individuals belonging to 389 species from nine major woody biomes in China, along with reduced sample size of hydraulic and leaf carbon economics data. We aimed to investigate the variation of πtlp across biomes varying in water availability.

MicroRNA-23a-5p regulates osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by targeting mitogen-activated protein kinase-13.

The molecular mechanisms of osteogenic differentiation of bone marrow-derived mesenchymal stem cells (BMSCs) remain to be fully elucidated. MicroRNAs (miRs) serve vital roles in the process of regulating osteogenic differentiation of BMSCs. The present study aimed to investigate the role of miR‑23a‑5p in osteogenic differentiation of human (h)BMSCs, and the underlying molecular mechanism.

[Cd(Ⅱ) Ion Adsorption and Sealing onto SBA-15 Mesoporous Particles and the Related Potential on Cd(Ⅱ) Polluted Soil Remediation].

Aiming to expand the utilization of porous silicate minerals in the remediation of heavy metal contaminated soil,the mesoporous material SBA-15 was successfully synthesized by using sodium silicate as silica source in this study.And the obtained SBA-15 samples were characterized by TEM,X-ray diffraction,N adsorption-desorption and FTIR.Furthermore,characterization of Cd (Ⅱ) adsorption and sealing performance onto SBA-15 were evaluated through batch experiment,and the remediation potential of Cd (Ⅱ) contaminated soil was investigated by brassica planting in a pot experiment.

[Effect of Alkali Solids Amendment on Sewage Sludge Aerobic Composting and the Potential of Related Products on Infertile Soil Amelioration].

Aiming to evaluate the influence of alkali solids amendment on the sewage sludge aerobic composting and to declare the potential of related composts on infertile soil amelioration, sewage sludge and sawdust mixture were amended with straw biochar, hardwood biochar, fly ash and lime by 10% addition ratio in dry weight during the aerobic composting process; finally, potential of the related composts on the infertile soil amelioration was investigated by pot experiment. The results showed that the alkali solids amendment could prolong the thermophilic phase, and promote the composting material heat inactivation. Addition of straw and hardwood biochar facilitated more than 21.

[Adsorption Cd from Solution by EDTA-modified Silicate Nanoparticles].

Silicate nanoparticles(nSiO) are a kind of widely used engineering material. In order to improve the Cd adsorption ability, the EDTA-modified nSiO nanoparticles were prepared by grafting method and characterized by TEM, N adsorption-desorption, FTIR, and TGA. The effects of solution pH, contact time, temperature and ionic strength were examined.

Different leaf cost-benefit strategies of ferns distributed in contrasting light habitats of sub-tropical forests.

Background And Aims: Ferns are abundant in sub-tropical forests in southern China, with some species being restricted to shaded understorey of natural forests, while others are widespread in disturbed, open habitats. To explain this distribution pattern, we hypothesize that ferns that occur in disturbed forests (FDF) have a different leaf cost-benefit strategy compared with ferns that occur in natural forests (FNF), with a quicker return on carbon investment in disturbed habitats compared with old-growth forests.

Methods: We chose 16 fern species from contrasting light habitats (eight FDF and eight FNF) and studied leaf functional traits, including leaf life span (LLS), specific leaf area (SLA), leaf nitrogen and phosphorus concentrations (N and P), maximum net photosynthetic rates (A), leaf construction cost (CC) and payback time (PBT), to conduct a leaf cost-benefit analysis for the two fern groups.

Temozolomide for Treating Malignant Melanoma.

Melanoma is one of the most malignant forms of skin cancer; with a rapidly increasing prevalence. Early-stage melanoma is curable, but advanced metastatic melanoma is almost always fatal, and patients with such advanced disease have short median survival. Surgery and radiotherapy play a limited role in the treatment of metastatic melanoma.

Gene Transcriptional and Metabolic Profile Changes in Mimetic Aging Mice Induced by D-Galactose.

D-galactose injection has been shown to induce many changes in mice that represent accelerated aging. This mouse model has been widely used for pharmacological studies of anti-aging agents. The underlying mechanism of D-galactose induced aging remains unclear, however, it appears to relate to glucose and 1ipid metabolic disorders.

Dacarbazine combined targeted therapy versus dacarbazine alone in patients with malignant melanoma: a meta-analysis.

Background: Malignant melanoma is the most aggressive and deadly form of skin cancer. Dacarbazine (DTIC) has been the approved first-line treatment for metastatic melanoma in routine clinical practice. However, response rates with single-agent DTIC are low.

Enhanced antitumor efficacy of a novel oncolytic adenovirus combined with temozolomide in the treatment of melanoma in vivo.

Purpose: The aim of this study was to investigate the effect of Ki67-ZD55-IL-24 with temozolomide (TMZ) against melanoma in mice.

Methods: Seventy-eight mice with subcutaneous injection of A375 cells (2 × 10(6)) into the right flank were randomized to receive phosphate buffered saline (PBS), Ki67-ZD55, Ki67-ZD55-IL-24, TMZ, TMZ + Ki67-ZD55, and TMZ + Ki67-ZD55-IL-24. Six mice were killed in each group 10 days after intervention for detecting IL-24 mRNA and protein expression.

Concurrent alterations of RAGE, RECK, and MMP9 protein expression are relevant to Epstein-Barr virus infection, metastasis, and survival in nasopharyngeal carcinoma.

This study aimed to concurrently investigate the expressions of receptor for advanced glycation end products (RAGE), reversion inducing cysteine-rich protein with Kazal motifs (RECK) and matrix metalloproteinase 9 (MMP9) in nasopharyngeal carcinoma (NPC) and their correlations with clinicopathological properties. Using immunohistochemistry, we found that RECK expression was downregulated in NPC tissues compared with chronic nasopharyngitis (CNT) tissues, while RAGE and MMP9 expressions were upregulated. We further found that RECK expression level was inversely correlated with MMP9 expression level in NPC, whereas RAGE expression level was positively correlated with MMP9 expression level.

Multiple pathogenic proteins implicated in neuronopathic Gaucher disease mice.

Gaucher disease, a prevalent lysosomal storage disease (LSD), is caused by insufficient activity of acid β-glucosidase (GCase) and the resultant glucosylceramide (GC)/glucosylsphingosine (GS) accumulation in visceral organs (Type 1) and the central nervous system (Types 2 and 3). Recent clinical and genetic studies implicate a pathogenic link between Gaucher and neurodegenerative diseases. The aggregation and inclusion bodies of α-synuclein with ubiquitin are present in the brains of Gaucher disease patients and mouse models.