Feasibility and Safety of Radiofrequency Ablation Guided by Bronchoscopic Transparenchymal Nodule Access in Canines.

Background: The treatment of pulmonary malignancies remains a challenge. The efficacy and safety of bronchoscopic radiofrequency ablation (RFA) for the treatment of lung cancer are not well elucidated.

Objective: This study aimed to evaluate the feasibility and safety of RFA guided by bronchoscopic transparenchymal nodule access (BTPNA) in vivo.

Effect of Nitrogen Flow Ratio on Composition, Microstructure, and Mechanical Properties of Cr-B-O-N Films Deposited by Pulsed Direct Current Magnetron Sputtering.

Nano-crystalline CrB₂ and Cr-B-O-N films with various nitrogen flow ratios were deposited using a pulsed direct current (PDC) magnetron sputtering technique. By means of electron probe micro-analysis, X-ray diffraction (XRD), X-ray photoelectron spectroscopy, scanning electron microscopy, high-resolution transmission electron microscopy (HRTEM), and atomic force microscopy, the influences of the nitrogen flow ratio on the phase constituents and microstructures of CrB₂/Cr-B-O-N films were systematically investigated. Mechanical properties including the hardness and elastic modulus were explored by a nano-indentation tester.

Anti-asthma effects of synthetic salidroside through regulation of Th1/Th2 balance.

Aim: The aim of the study was to investigate the effect and mechanism of action of synthetic salidroside in an ovalbumin (OVA)-induced asthma model in mice.

Method: BALB/c mice were sensitized with an intraperitoneal injection of ovalbumin (OVA) to induce a mouse model of asthma in paracmasis. The mice were treated with dexamethasone as the positive control.