-related prognostic gene signature correlates with immune microenvironment in gastric cancer.

Background: Chromobox () proteins are important Polycomb family proteins in the development of gastric cancer. Nonetheless, the relationship between and gastric cancer microenvironment remains unclear.

Methods: Multiple databases were used for the analysis of expression and clinical value in gastric cancer patients.

Early intervention with Di-Dang Decoction prevents macrovascular fibrosis in diabetic rats by regulating the TGF-β1/Smad signalling pathway.

Macroangiopathy is a complication of Type II Diabetes Mellitus (T2DM), which is mainly caused by fibrosis of blood vessels. Using T2DM rat models, we investigated whether the traditional Chinese medicine, Di-Dang Decoction (DDD), exhibited anti-fibrotic actions on great vessels. T2DM rats were randomly divided into non-intervention group, early-, middle-, late-stage DDD intervention groups and control groups, including pioglitazone group and aminoguanidine group.