Effects of gender-affirming hormone therapy on lower urinary tract symptoms and sexual function among transgender individuals.

Objective: Gender-affirming hormone therapy (GAHT) includes estrogen preparations and androgen inhibitors for transgender women, and testosterone preparations for transgender men. The aim of the study was to investigate possible effects of GAHT on lower urinary tract symptoms (LUTS) and sexual function among transgender individuals.

Methods: Fifty-one transgender men and 47 transgender women were prospectively recruited.

Safety and Efficacy of Minimally Invasive Sacrospinous Ligament Fixation for Apical Pelvic Organ Prolapse in Older Women.

This study aimed to evaluate the safety and efficacy of minimally invasive sacrospinous ligament (SSL) fixation of apical pelvic organ prolapse (POP) in older patients compared to younger patients. A cohort of 271 older (≥65 years) patients (mean age 71.8 ± 5.

The EnPlace sacrospinous ligament fixation-A novel minimally invasive transvaginal procedure for apical pelvic organ prolapse repair: Safety and short-term outcome results.

Objective: The EnPlace device is a novel minimally invasive tool allowing transvaginal sacrospinous ligament (SSL) fixation of apical pelvic organ prolapse (POP). The study aimed to investigate the safety and short-term efficacy of the EnPlace SSL fixation for significant apical POP repair.

Methods: A retrospective cohort study of 123 consecutive patients (mean age 64.

High Incidence of Obstetric Anal Sphincter Injuries among Immigrant Women of Asian Ethnicity.

(1) Background: Obstetric anal sphincter injuries (OASI) may complicate vaginal deliveries. The aim of the present study was to explore the incidence and clinical characteristics of OASI among Asian women living in a Western country compared to local Caucasian women. (2) Methods: A retrospective cohort study of 380 women diagnosed with OASI, following singleton vaginal deliveries, during a 10-year period (January 2011 to December 2020).

Substantial Obstetric Anal Sphincter Injury during Vacuum Assisted Delivery: An Obstetrical Issue or Device Related?

Background: Obstetric anal sphincter injuries (OASIS) might be associated with long-term urinary and anorectal morbidities. The aim of the study was to investigate the risk factors and clinical implications of OASIS associated with vacuum-assisted deliveries versus normal vaginal deliveries.

Methods: A series of 413 consecutive OASIS cases were retrospectively analyzed.

The Manchester operation - is it time for it to return to our surgical armamentarium in the twenty-first century?

We conducted a study to assess the efficacy and outcome results of Manchester operation for women with symptomatic elongation of uterine cervix between 2010 and 2020. Forty-five women were enrolled. Mean age was 54.

A tailored flexible vaginal pessary treatment for pelvic organ prolapse in older women.

Objectives: To present a flexible protocol of vaginal pessaries for older women with significant pelvic organ prolapse (POP).

Design: A prospective cohort study of 140 consecutive older women (aged ≥65 years) with significant POP treated with individually fitted vaginal pessaries. After initial insertion, each patient was invited for a first evaluation after 1 month and subsequent follow-ups at increasing intervals of 1 month.

The Effect of a Sharp Increase in Estrogen Levels on Overactive Bladder Symptoms in Women Undergoing Ovulation Induction.

Objective: To assess the effect of a sharp increase in estrogen levels on overactive bladder (OAB) symptoms among women undergoing ovulation induction.

Methods: 100 consecutive women (mean age 36.9 ± 5.

Ten-year subjective outcome results of the retropubic tension-free vaginal tape for treatment of stress urinary incontinence.

Study Objective: To assess the 10-year subjective outcome of use of retropubic tension-free vaginal tape (TVT).

Design: Structured telephone interview (Canadian Task Force classification II-3).

Setting: Universitiy-affiliated tertiary medical center.

Long-term outcome of transobturator tension-free vaginal tape: efficacy and risk factors for surgical failure.

Purpose: To assess the 5-year efficacy of the inside-out transobturator tension-free vaginal tape (TVT-O) for the treatment of stress urinary incontinence (SUI) and to explore possible predictors for long-term failure.

Methods: Sixty-five consecutive patients who underwent TVT-O were prospectively enrolled. Patients who required concomitant anterior or apical pelvic organ prolapse repair or both and those with urodynamic occult SUI were excluded.

Third- and fourth-degree perineal tears: prevalence and risk factors in the third millennium.

Objective: We sought to assess the modern prevalence and risk factors for third- and fourth-degree perineal tears.

Study Design: The study population comprised 38,252 women who delivered in one medical center, from January 2005 through December 2009, and met the following inclusion criteria: singleton pregnancy, vertex presentation, and vaginal delivery. Of these, 96 women (0.

"Inside-out" transobturator tension-free vaginal tape for management of occult stress urinary incontinence in women undergoing pelvic organ prolapse repair.

Objectives: To assess the safety and effectiveness of the "inside-out" transobturator tension-free vaginal tape procedure for the management of occult stress urinary incontinence (SUI) in clinically continent women undergoing prolapse repair.

Methods: A total of 117 consecutive continent women (mean age and parity 66.8 ± 9.

Protracted postpartum urinary retention: the importance of early diagnosis and timely intervention.

Aims: To evaluate the prevalence and obstetric risk factors of protracted postpartum urinary retention, beyond the third postpartum day.

Methods: Thirty thousand seven hundred fifty-seven consecutive women delivered in Lis maternity hospital during June 2006 to June 2009. The term "protracted postpartum urinary retention" was defined as the absence of adequate voiding beyond the third postpartum day.

The safety and efficacy of the "inside-out" trans-obturator TVT in elderly versus younger stress-incontinent women: a prospective study of 353 consecutive patients.

Objectives: To analyze the safety and efficacy of the trans-obturator tension-free vaginal tape (TVT-O) in elderly versus younger stress-incontinent women.

Methods: Ninety-seven consecutive elderly, aged 70 and older, and 256 younger women (mean age 75 and 55 years, respectively) who underwent TVT-O for urodynamically confirmed stress urinary incontinence (SUI) were prospectively enrolled. Concomitant pelvic organ prolapse (POP) repair was performed in 90% of the elderly and 70% of the younger women.

Bladder perforation during tension-free vaginal tape surgery: does it matter?

Objective: To analyze the incidence, possible risk factors, preoperative morbidity and outcome results in tension-free vaginal tape (TVT) cases complicated by lower urinary tract injury in a large, heterogeneous, consecutive group of women.

Study Design: Four hundred sixty consecutive women who underwent TVT surgery for correction of urodynamically proven stress urinary incontinence were enrolled prospectively. All the procedures were performed at 1 center by 3 experienced surgeons.

First vaginal delivery at an older age: Does it carry an extra risk for the development of stress urinary incontinence?

Aims: First delivery at an older age is not an uncommon event in modern obstetric practice. The present study was undertaken to compare the prevalence of postpartum stress urinary incontinence (SUI) according to maternal age and mode of delivery.

Methods: Fifty two consecutive elderly primiparae (mean age 40.

[Post partum anal incontinence].

Vaginal delivery is one of the main causes of anal incontinence. While previously postpartum anal incontinence was attributed to neurological damage to the pelvic floor and the rectal sphincter, today we know that mechanical injury plays an important role, especially when symptoms start soon after delivery. Risk factors for postpartum fecal incontinence are: forceps delivery, nulliparity, birth weight over 4 kilograms and persistent occiput posterior presentation of the fetal head.

Tension-free vaginal tape in the elderly: is it a safe procedure?

Objectives: To analyze the safety and efficacy of tension-free vaginal tape (TVT) surgery in elderly versus younger women with stress urinary incontinence (SUI).

Methods: A total of 157 consecutive elderly women, aged 70 years and older, and 303 younger women (mean age, 74.8 and 57.

[Pregnancy, labor and delivery: the pelvic floor injury].

The association between pregnancy, labor and delivery, and pelvic floor injury is well known. Pregnancy itself may be associated with some injury, but the main damage occurs during vaginal delivery. It is well documented that vaginal delivery may cause denervation of the pelvic floor as well as direct injury to muscles and connective tissue.

Early postpartum voiding dysfunction: incidence and correlation with obstetric parameters.

Objective: To investigate the incidence and obstetric risk factors in early postpartum voiding dysfunction.

Study Design: Two hundred seventy-seven consecutive women in the early postpartum period were prospectively enrolled. Evaluation included history, physical examination, urinary questionnaire and non-invasive uroflowmetry measurements.

Tension-free vaginal tape (TVT) for the treatment of occult stress urinary incontinence in women undergoing prolapse repair: a prospective study of 100 consecutive cases.

Aims: Clinically continent women with genitourinary prolapse and occult stress urinary incontinence (SUI) are considered to be at high risk of developing symptomatic SUI once the prolapse is repaired. We studied the efficacy and safety of tension-free vaginal tape (TVT) procedure in preventing postoperative SUI in these women.

Methods: One hundred consecutive women (mean age 66.

Surgical complications and medium-term outcome results of tension-free vaginal tape: a prospective study of 313 consecutive patients.

Objective: A prospective study was undertaken to examine the incidence of surgical complications and medium-term outcomes of tension-free vaginal tape (TVT) surgery in a large, heterogeneous group of stress-incontinent women.

Methods: Surgery was tailored according to preoperative clinical and urodynamic findings: stress-incontinent women underwent TVT surgery, whereas those with concomitant urogenital prolapse underwent combined TVT and prolapse repair. Post-operatively the patients were scheduled for evaluation at 1, 3, 6, and 12 months, and annually thereafter.