Publications by authors named "Ronald S Fernando"
Baseline Features and Reasons for Nonparticipation in the Colonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM) Study, a Colorectal Cancer Screening Trial.
Douglas J Robertson Jason A Dominitz Alexander Beed Kathy D Boardman Barbara J Del Curto Fernando V Ona Ronald S Fernando
JAMA Netw Open
July 2023
Article Synopsis
- The CONFIRM trial aimed to compare the effectiveness of annual fecal immunochemical tests (FIT) versus colonoscopies in reducing colorectal cancer mortality, enrolling over 50,000 veterans between May 2012 and December 2017.
- The study analyzed participant demographics and examined reasons for those who chose not to participate, highlighting a mix of preferences for either colonoscopy or stool tests based on geographic and temporal factors.
- Among the 50,126 participants recruited, there was a diverse representation, and the study also noted that 11,109 eligible individuals opted out of participation for various reasons, with insights gathered via case report forms.
Article Synopsis
- Heartburn that doesn't improve with proton-pump inhibitors (PPIs) is a common issue, possibly needing alternative treatments like surgery or different medications, as there’s no proven effective solution yet.
- In a study, 366 patients with persistent heartburn were initially tested with omeprazole; those who didn’t find relief underwent various diagnostic procedures before being randomly assigned to different treatment groups.
- The results showed that surgical treatment was significantly more effective than active medical treatment or placebo, with 67% of surgical patients reporting success compared to 28% in the active treatment group.