Publications by authors named "Ronald K McMillan"
Six-year follow-up of a world record-breaking master marathon runner.
J Appl Physiol (1985)
November 2024
Article Synopsis
- Older athletes, like the 76-year-old runner who broke a marathon record, often run slower as they age, mainly because their body uses oxygen less effectively.
- Even though this runner still competes at a high level, his ability to take in oxygen (V̇Omax) dropped by about 15% over a 6-year period.
- This study helps us understand how aging affects athletic performance and shows that even elite athletes can experience changes as they get older.
Rodent studies demonstrated specialized sodium chloride (NaCl) sensing neurons in the circumventricular organs, which mediate changes in sympathetic nerve activity, arginine vasopressin, thirst, and blood pressure. However, the neural pathways involved in NaCl sensing in the human brain are incompletely understood. The purpose of this pilot study was to determine if acute hypernatremia alters the functional connectivity of NaCl-sensing regions of the brain in healthy young adults.
View Article and Find Full Text PDFBackground: Salt sensitivity and inverse salt sensitivity [ISS; a reduction in blood pressure (BP) on a high sodium diet] are each associated with increased incidence of hypertension. The purpose of this analysis was to determine the prevalence of ISS in normotensive adults and whether ISS is associated with any demographic characteristic(s).
Methods: Healthy normotensive, nonobese adults [ n = 84; 43 women; age = 37 ± 13 years; baseline mean arterial pressure (MAP) = 89 ± 8 mmHg] participated in a controlled feeding study, consuming 7-day low-sodium (20 mmol sodium/day) and high-sodium (300 mmol sodium/day) diets.