Publications by authors named "Ronald Fernandes"

Cancer immunotherapy has long been an essential segment of current research and presents several problems to contemporary medicine. Though their precise roles are still elusive, recent studies have highlighted the importance of both innate and adaptive immune defence systems in the development and management of cancer. The immune system plays a crucial role in cancer prevention and control by identifying and eliminating abnormal cells.

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Background: Lutein, a carotenoid compound, has previously been studied for its antioxidant and medicinal properties as well as the moderate protection it confers against gamma radiation. This study aimed at evaluating the effects of lutein against radiation-induced hematological and biochemical changes in mice.

Methods: The optimized dose of the compound was orally administered for 15 days, and the mice were irradiated (6 Gy) on day 15 after the administration of the compound.

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Objectives: Radiation-induced hematological, biochemical, and cytogenetic damages to the normal cells are major concerns in the field of radiotherapy. The carotenoids and their derivatives have been the source of antioxidants with wide range of medicinal applications. The objective is to evaluate the protective effects of lutein, a carotenoid, against radiation-induced cellular and tissue damages.

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