Effect of immediate postoperative intracameral tissue plasminogen activator (tPA) on anterior chamber fibrin formation in dogs undergoing phacoemulsification.

Objective: To evaluate the postoperative effect of intracameral tPA (alteplase; Activase®, Genentech, San Francisco, CA), administered at immediate conclusion of phacoemulsification, on anterior chamber fibrin formation in dogs.

Procedures: Forty-one dogs (82 eyes) undergoing bilateral phacoemulsification received 25 μg/0.1 mL intracameral tPA in one eye and 0.

Preoperative findings and visual outcome associated with retinal reattachment surgery in dogs: 217 cases (275 eyes).

Objective: Report the correlation of pre-operative findings with visual outcome in dogs undergoing retinal reattachment surgery for giant retinal tears.

Procedures: Retrospective analysis of dogs that underwent pars plana vitrectomy (PPV) with silicone oil (SiO) tamponade and endolaser retinopexy at one institution. Recorded parameters included signalment, etiology, and duration of retinal detachment, observable retinal tissue architecture, visual reflexes, lens status, presurgical aqueous flare, visual status postoperatively, and complications.

Analysis of the transport of and cytotoxic effects for nalbuphine solution in corneal cells.

Objective: To assess the in vitro effects of various nalbuphine concentrations on viability and wound healing ability of corneal cells and potential drug transport through the corneal epithelium.

Sample: Cultured canine and human corneal epithelial cells (CECs) and cultured canine corneal stromal fibroblasts.

Procedures: CECs and stromal fibroblasts were exposed to nalbuphine (concentration of solutions ranged from 0% to 1.