Similar expression pattern of NHERF1 and EZRIN in papillary but not in solid areas of human serous ovarian carcinomas.

NHERF1 is an adaptor protein expressed in the apical membrane of polarized epithelia, which interacts with the EZRIN-Radixin-Moesin (ERM) family of proteins connecting signaling pathways to the cell cytoskeleton. NHERF1 and EZRIN cooperate in the maintenance of the apical microvilli in polarized epithelial cells. In several types of cancers, NHERF1 and EZRIN are displaced from the apical compartment to the cytoplasm and nuclei of cancer cells.

Experimental set up for the irradiation of biological samples and nuclear track detectors with UV C.

Aim: In this work we present a methodology to produce an "imprint" of cells cultivated on a polycarbonate detector by exposure of the detector to UV C radiation.

Background: The distribution and concentration of (10)B atoms in tissue samples coming from BNCT (Boron Neutron Capture Therapy) protocols can be determined through the quantification and analysis of the tracks forming its autoradiography image on a nuclear track detector. The location of boron atoms in the cell structure could be known more accurately by the simultaneous observation of the nuclear tracks and the sample image on the detector.

Simultaneous Observation of Cells and Nuclear Tracks from the Boron Neutron Capture Reaction by UV-C Sensitization of Polycarbonate.

The distribution of boron in tissue samples coming from boron neutron capture therapy protocols can be determined through the analysis of its autoradiography image on a nuclear track detector. A more precise knowledge of boron atom location on the microscopic scale can be attained by the observation of nuclear tracks superimposed on the sample image on the detector. A method to produce an "imprint" of cells cultivated on a polycarbonate detector was developed, based on the photodegradation properties of UV-C radiation on this material.

Osteosarcoma of the jaw: an analysis of a series of 74 cases.

Aims: To analyse a series of cases of osteosarcoma of the jaw.

Methods And Results: The study included 74 cases of osteosarcoma of the jaw. Their clinical, radiographic and histopathological features were analysed, and their frequency with respect to aggressive and malignant pathologies of the jaw was determined.

Technical aspects of core needle biopsy and fine needle aspiration in the diagnosis of bone lesions.

Objective: Percutaneous needle biopsy is an effective and safe technique for obtaining diagnostic material from bone lesions.

Study Design: We describe the technical details of fine needle aspiration and core needle biopsy performed in our laboratory of orthopedic pathology.

Results: With these procedures, we obtained accurate diagnosis in 83% of 7,375 cases, sent by different orthopedic centers in our country, over a period of 21 years (1986-2007).

Expression of ezrin and metastatic tumor antigen in osteosarcomas of the jaw.

Aims And Background: Ezrin is a membrane-cytoskeleton linker protein involved in regulation of the growth and metastatic behavior of cancer cells. Metastatic tumor antigen (MTA) is a potential metastasis-associated protein. The objective of this study was to evaluate the expression of ezrin and MTA and their correlation with clinicopathological features in osteosarcomas of the jaw.

Clinical features and evolution of oral cancer: A study of 274 cases in Buenos Aires, Argentina.

Unlabelled: Oral Squamous Cell Carcinoma has a low survival rate, 34 to 66% five-year survival after initial diagnosis, due to late diagnosis.

Objectives: The aim of the present study was to examine the clinical features and evolution of oral cancer in the University of Buenos Aires.

Study Design: 274 patients with primary oral carcinoma, over the 1992-2000 period were included in the study.

Biodistribution of titanium dioxide from biologic compartments.

The layer of titanium dioxide (TiO(2)) of the implant is chronically exposed to the internal electrolyte milieu in the peri-implant biological compartment. Corrosion results from electrochemical attack and ensuing gradual degradation of the metallic materials and is thus of biological interest when these biomaterials are employed in clinical implantology. Herein we evaluated and compared the chronic effect and the biodistribution of TiO(2) administered subcutaneously or intraperitoneally.

Evaluation of nucleolar organizer regions in maxillary osteosarcoma.

Maxillary osteosarcomas are a relatively frequent malignant tumor of the oral cavity. Similarly to other skeletal osteosarcomas, they exhibit different cellular differentiation patterns, i.e.

An experimental study of the dissemination of Titanium and Zirconium in the body.

Metallic implants can generate and release titanium oxide (TiO(2)) and zirconium oxide (ZrO(2)) to the tissues. These products can accumulate locally or disseminate systemically. The aim of the present study was to assess the distribution of TiO(2) and ZrO(2) administered intraperitoneally to rats.

Macrophages related to dental implant failure.

Purpose: The aim of this study was to evaluate, histologically and quantitatively, the presence of macrophages loaded with metallic particles in the periimplant soft tissues of failed titanium (Ti) dental implants.

Materials And Methods: The study was performed on sections of metallic Ti implants embedded in methyl methacrylate resin that exhibited macrophages in the soft tissues contiguous with the implant. The volume of periimplant soft tissue was evaluated, and the number of macrophages was determined.