Publications by authors named "Romuald Tematio Fouedjou"
Article Synopsis
- Traditional medicine has utilized various species for treating ailments like coughs, dysentery, and fevers, with around 26 recognized species worldwide.
- This review highlights the traditional uses, chemical makeup, and biological effects of plants from a specific genus, revealing 98 compounds related to these uses.
- Some isolates and extracts from these species show promising activities, including antioxidant and antimicrobial effects, indicating their potential for discovering new bioactive compounds despite limited research.
Unlabelled: In silico studies performed on the metabolites of four Cameroonian medicinal plants with a view to propose potential molecules to fight against COVID-19 were carried out. At first, molecular docking was performed for a set of 84 selected phytochemicals with SARS-CoV-2 main protease (PDB ID: 6lu7) protein. It was further followed by assessing the pharmacokinetics and pharmacological abilities of 15 compounds, which showed low binding energy values.
View Article and Find Full Text PDFWe report the major conclusions of the online open-access workshop "Computational Applications in Secondary Metabolite Discovery (CAiSMD)" that took place from 08 to 10 March 2021. Invited speakers from academia and industry and about 200 registered participants from five continents (Africa, Asia, Europe, South America, and North America) took part in the workshop. The workshop highlighted the potential applications of computational methodologies in the search for secondary metabolites (SMs) or natural products (NPs) as potential drugs and drug leads.
View Article and Find Full Text PDFThe polar fraction of the MeOH extract of the roots of subsp. (Pourr.) Briq.
View Article and Find Full Text PDFCoronavirus disease 2019 (COVID-19) is an ongoing pandemic instigated by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) which changed the daily train of the world's population and cause several dead. Despite the significant efforts made in developing vaccines and therapeutic drugs, there is currently no available effective treatment against this new coronavirus infection, hence the need to continue research which is aimed at limiting the progression of this virus. The present study which has as objective to carry out studies on the metabolites of some Cameroonian medicinal plants of the family with a view to propose potential molecules to fight against COVID-19.
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