Publications by authors named "Romina Piscitello-Gomez"
Article Synopsis
- Researchers are investigating how morphogenetic movements are coordinated during the development of the wing in pupae, focusing on the mechanical and cellular behaviors involved.
- Previous studies indicated that wing morphogenesis includes behaviors for stress relaxation and other patterned actions, but this new research shows these active cellular behaviors do not rely on a key signaling pathway called core planar cell polarity (PCP).
- Experiments demonstrated that while core PCP mutations could alter quick responses to certain disturbances, they do not significantly impact the overall mechanics of tissue shape changes during wing development.
Tissue organization is often characterized by specific patterns of cell morphology. How such patterns emerge in developing tissues is a fundamental open question. Here, we investigate the emergence of tissue-scale patterns of cell shape and mechanical tissue stress in the wing imaginal disc during larval development.
View Article and Find Full Text PDFStudying how epithelia respond to mechanical stresses is key to understanding tissue shape changes during morphogenesis. Here, we study the viscoelastic properties of the Drosophila wing epithelium during pupal morphogenesis by quantifying mechanical stress and cell shape as a function of time. We find a delay of 8 h between maximal tissue stress and maximal cell elongation, indicating a viscoelastic deformation of the tissue.
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