Grafting of tooth extraction socket with inorganic bovine bone or bioactive glass particles: comparative histometric study in rats.

Purpose: To compare histometrically, in rats, the bone healing after grafting the incisor extraction sockets with inorganic bovine bone or bioactive glass particles.

Material: The volume fraction of grafted materials and alveolar healing components was estimated in histologic images at the end of the second and ninth weeks postoperatively by a differential point-counting method.

Results: Both materials were histologically observed partially filling the cervical alveolar third and, although evoking neither a foreign body reaction nor a persisting inflammatory response, delayed new bone formation in trial areas around their particles.

Alveolar wound healing after implantation with a pool of commercially available bovine bone morphogenetic proteins (BMPs): a histometric study in rats.

The capacity of a commercially available pool of bovine bone morphogenetic proteins (BMPs) to stimulate osteogenesis in the rat alveolar healing was investigated by histometric analysis. Male rats were anesthetized and had their upper incisor extracted. A pool of purified bovine BMPs adsorbed to microgranular resorbable hydroxyapatite was agglutinated with bovine collagen and saline before implantation into the alveolar socket.