Cytotoxycity and antiplasmodial activity of phenolic derivatives from Albizia zygia (DC.) J.F. Macbr. (Mimosaceae).

Background: The proliferation and resistance of microorganisms area serious threat against humankind and the search for new therapeutics is needed. The present report describes the antiplasmodial and anticancer activities of samples isolated from the methanol extract of Albizia zygia (Mimosaseae).

Material: The plant extract was prepared by maceration in methanol.

Caffeate and piperidine-3-ol derivatives from the stem bark of .

A new caffeate derivative from the ethanol extract of the stem bark of DC. is described herein along with the known secondary metabolites spectaline (), -6-cassine (), 3--methyl--inositol (), monobehenin (), octyl nonadecyloate (), -sitosterol (), stigmasterol () and sitosterol 3---D-glucopyranoside (). The chemical structures were elucidated by means of various spectroscopic and spectrometric techniques.