Publications by authors named "Romario Thomas"
Article Synopsis
- Anxiety is a common non-motor symptom of Parkinson's disease that can begin before noticeable motor symptoms, with a higher prevalence in females despite the disease being more common in males.
- A study used young adult mice with a specific mutation related to Parkinson's to investigate differences in stress-induced anxiety behaviors between male and female subjects, revealing no baseline differences in anxiety responses.
- Following chronic stress, male mice showed different responses compared to their wildtype counterparts but female mice exhibited similar anxiety reactions to stress regardless of mutation, highlighting a significant sex-specific difference in how the mutation affects stress-related anxiety behaviors.
Anxiety is a psychiatric non-motor symptom of Parkinson's that can appear in the prodromal period, prior to significant loss of brainstem dopamine neurons and motor symptoms. Parkinson's-related anxiety affects females more than males, despite the greater prevalence of Parkinson's in males. How stress, anxiety and Parkinson's are related and the basis for a sex-specific impact of stress in Parkinson's are not clear.
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