Publications by authors named "Romano V"
Purpose: To quantify the effect of cataract surgery on cornea shape.
Methods: Patients undergoing cataract surgery with standardised 2.75 mm surgical incisions at 110 degrees with a side port at 50 degrees were included.
Background: To analyse the effect of suprachoroidal injection (SChI) of triamcinolone acetonide (TA) on macular thickness (CRT), ectopic inner foveal layer thickness (EIFL-T) and best corrected visual acuity (BCVA) in pseudophakic patients undergoing vitrectomy for epiretinal membrane (iERM) compared to intravitreal injection of TA (IVTA).
Methods: Prospective matched comparison of patients undergoing vitrectomy for Govetto stage 3 and 4 iERM. 25 eyes receiving IVTA (G-1) were compared to 23 eyes receiving SChI-TA (G-2) during vitrectomy.
Purpose: To extract conjunctival bulbar redness from standardized high-resolution ocular surface photographs of a novel imaging system by implementing an image analysis pipeline.
Methods: Data from two trials (healthy; outgoing ophthalmic clinic) were collected, processed, and used to train a machine learning model for ocular surface segmentation. Various regions of interest were defined to globally and locally extract a redness biomarker based on color intensity.
The surface behaviours of humpback whales were studied in the presence of a whale-watching vessel at Nosy Be (Madagascar) during whale-watching activities, in order to characterise the ethogram of these animals. Data were collected from July to October 2018. Of the 75 total trips, humpback whales were observed 68 times and different types of aggregations were observed: Groups (33.
View Article and Find Full Text PDFBackground: Left ventricular obstruction (LVO) is an infrequent complication following transcatheter aortic valve replacement (TAVR) that can lead to severe hemodynamic decompensation. Previous studies have analyzed the pathophysiology of this clinical entity; however, little is known about the anatomical characteristics as assessed by computational tomography (CT) of patients at risk.
Methods: Data from 349 patients were retrospectively analyzed from a single center registry of patients undergoing TAVR at San Raffaele Hospital, Milan, Italy, between January 2020 and December 2021.
As brain-machine interfaces (BMI) are growingly used in clinical settings, understanding how to apply brain stimulation is increasingly important. Despite the emergence of optogenetic techniques, ethical and medical concerns suggest that interventions that are safe and non-invasive, such as Transcranial Alternating Current Stimulation (tACS), are more likely to be employed in human in the near future. Consequently, the question of how and where to apply current stimulation is becoming increasingly important for the efficient neuromodulation of both neurological and psychiatric disorders.
View Article and Find Full Text PDFPurpose: To identify areas of consensus among experts on the performance of endothelial keratoplasty by using a modified Delphi approach, to help create a framework for novice surgeons to adopt these procedures.
Methods: Thirty-one international experts in endothelial keratoplasty participated. Two rounds of electronic survey were followed by a hybrid, virtual meeting.
Background: Transcatheter aortic valve replacement (TAVR)-in-TAVR within index supra-annular transcatheter heart valves (THVs) and high-risk anatomy can compromise coronary perfusion and re-access.
Case Summary: An 80-year-old male presented with acute heart failure caused by degeneration of an Evolut R THV, leading to severe aortic regurgitation. Aortic computed tomography imaging revealed a high-risk anatomy characterized by the index THV's commissural plane being placed above the coronary ostia and a valve-to-aorta distance of less than 2 mm, resulting not eligible for redo-TAVR according to recent literature.
Background: Transcatheter aortic valve replacement (TAVR) in patients with bicuspid aortic valve (BAV) disease is still burdened by a non-negligible rate of stroke and permanent pacemaker implantation (PPI). These suboptimal results, possibly related to the unique BAV anatomy, might suggest the use of a different sizing method in this setting. The aim of our study is to evaluate whether the application of the supra-annular LIRA method might improve clinical outcomes in this population.
View Article and Find Full Text PDFPurpose: To compare the aberrometric profile of the Artisan Aphakia lens (Opthec BV) and transscleral plug FIL-SSF lens (Soleko) and to assess the impact of tilt and decentration on their optical performance.
Methods: This retrospective observational study was conducted at Azienda Ospedaliera Universitaria Careggi, Florence, Italy, with a consecutive cohort of aphakic eyes undergoing secondary lens implantation with an Artisan or FIL-SSF lens. Wavefront analysis was performed using a pyramidal wavefront-based aberrometer (Osiris-T; CSO).
: This study aimed to describe the outcomes of a staged procedure combining Descemet membrane endothelial keratoplasty (DMEK) and sutureless scleral fixation (SSF) of a one-piece intraocular lens (IOL) in a case series. Co-performing endothelial keratoplasty (EK) and SSF is associated with intraoperative and postoperative complications such as graft deployment difficulties, air migration, graft detachment, and IOL opacification or tilt, all of which are evaluated in this study. This is a retrospective observational case series.
View Article and Find Full Text PDFPurpose: To describe an early sterile keratolysis associated with a decellularized porcine corneal inlay implant for keratoconus.
Methods: This is a case report of a 23-year-old man with keratoconus who underwent lenticular intrastromal keratoplasty in his OD. Within 4 weeks, the patient presented with anterior sterile keratolysis and partial inlay extrusion, leading to surgical inlay removal.
Article Synopsis
- * Cardiovascular events are the most common life-threatening complications, including oculocardiac reflex and iatrogenic vascular air embolism, which can lead to severe consequences like respiratory distress.
- * The review discusses potential complications, focusing on their causes, risk factors, symptoms, and management strategies, with particular attention to rare but serious infections like necrotizing fasciitis.
Purpose: To provide a detailed description of the recommended surgical technique for gas injection during Descemet's Membrane Endothelial Keratoplasty (DMEK) surgery and highlight intraoperative sign that emerged in case of fluid retention in the interface.
Methods: Gas injection recommended surgical technique is 2 steps procedure using a 1 ml syringe: the first step consists in injecting centrally to the graft and very slowly a bubble of gas smaller than the DMEK graft size, the second step, after checking the absence of fluid interface (no bagel sign), consists in enlarging the gas bubble to the desired filling.
Results: Bagel sign allows surgeons to look for interface fluid and correct for potential issues leading to graft detachment.
: The objective of this study was to examine the morphological corneal changes and outcomes following the implantation of an artificial endothelial layer (EndoArt) in patients with chronic corneal oedema. : A systematic review of the literature was conducted alongside a detailed analysis of two clinical cases with chronic corneal oedema that were treated using EndoArt. Our experience with these two cases is included to provide practical insights and real-world outcomes.
View Article and Find Full Text PDFPurpose: The aim of this study was to assess the outcomes of off-centered Descemet membrane endothelial keratoplasty (DMEK) grafts compared to descemetorhexis.
Methods: This is a retrospective case series of DMEK procedures conducted between June 2022 and July 2023 with postoperative graft decentration, characterized by a gap between the graft and descemetorhexis edge.
Results: Eight eyes of 8 patients met the inclusion criteria.
Purpose: To investigate the role of preoperative posterior stromal ripples (pre-PSR) on visual acuity recovery after Descemet membrane endothelial keratoplasty (DMEK).
Methods: This is a comparative case series retrospectively analyzing patients who underwent DMEK. Electronic records and imaging of DMEK patients were reviewed.
The two surgical options for mitral valve regurgitation are replacement and repair, with annuloplasty being the cornerstone of correction. In cases of repair failure, especially in high surgical risk patients, transcatheter mitral valve-in-ring (MViR) procedures represent emerging and challenging options. Among the several complications linked to this treatment, this paper delves into the role that native mitral leaflets may play in precipitating acute bioprosthesis dysfunction in the MViR procedure.
View Article and Find Full Text PDFGunshot wound morphology and gunshot residues (GSRs) evaluation have been poorly investigated in veterinary forensic pathology. The aims of the present study were to assess the gunshot wound morphology in animals and evaluate the detectability of lead deriving from GSRs using colorimetric techniques. To these aims, cadavers were divided into four different groups.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to examine whether using non-orthogonal correction (NOC) lenses could enhance visual acuity and perceived image quality for patients with keratoconus.
- Researchers tested 18 participants and their 23 eyes opted for NOC lenses, finding that 61% of eyes showed improved best-corrected visual acuity (BCVA), and many reported better letter clarity and less ghosting.
- The findings suggest that NOC lenses can be an effective option for correcting irregular astigmatism in keratoconus patients, with strong interest from participants for potential future use in spectacles.
Article Synopsis
- Metalloporphyrins with open-shell transition metals like Ni(II) have a fast excited-state relaxation mechanism, which is explored in a nanographene-Ni(II) porphyrin conjugate.
- Using variable temperature transient absorption and global fit analysis, the study reveals that after photoexcitation, vibrational cooling occurs in 1.6 ps, followed by a brief 20 ps window where some excited states decay radiatively before intersystem crossing.
- At low temperatures, two relaxation pathways from the lowest triplet state to the ground state are identified: a slow process over 1.6 ns and a faster route influenced by a conical intersection, important for applications in energy harvesting and optoelectronics.
Article Synopsis
- - Deep anterior lamellar keratoplasty (DALK) is a surgical technique for treating corneal disorders without affecting the endothelium, which helps prevent rejection and late graft failure compared to traditional penetrating keratoplasty (PK).
- - The introduction of the big-bubble technique (BBT) improved the efficiency and consistency of DALK by using air to separate corneal layers, resulting in high-quality grafts comparable to PK.
- - Understanding the anatomy behind BB formation, including the significance of Dua's layer, is essential for successful DALK procedures; ongoing improvements in BBT are increasing its use in corneal transplants with healthy endothelium.