Publications by authors named "Romane Teshima"

Article Synopsis
  • This review examines the links between generalized pustular psoriasis (GPP) and various systemic diseases, indicating that GPP has far-reaching health impacts beyond skin issues.
  • It emphasizes the role of specific cytokines, like IL-17 and IL-36, in GPP's pathophysiology and their potential contributions to complications in cardiovascular, liver, kidney, lung, and skeletal health.
  • The findings suggest a need for a holistic treatment approach that considers both skin and systemic health challenges associated with GPP to improve patient care and outcomes.
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Autoimmune diseases often co-occur due to shared immunological mechanisms, necessitating strategic treatment approaches to manage overlapping conditions without exacerbating each other. A 75-year-old male with a history of psoriasis vulgaris and bullous pemphigoid (BP) developed new-onset pustular psoriasis under systemic corticosteroid therapy, which is known to potentially worsen psoriasis into its pustular form. Histological examination confirmed the diagnosis, showing features typical of pustular psoriasis.

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Dermatofibrosarcoma protuberans (DFSP) is a rare and infiltrative soft tissue tumor. Our report details a distinctive case of DFSP with pan-TRK positivity in the right nasal dorsum of a 46-year-old female. Histological analysis identified fusion gene involvement in this patient, detectable through pan-TRK immunostaining.

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Langerhans cell histiocytosis (LCH) is a clonal proliferative disease of immature Langerhans cells that expand in various organs, leading to organ and tissue dysfunction. Although LCH is most commonly seen in children under the age of three, a small number of cases of congenital LCH have been described. With a review of the literature on congenital LCH with lung and skin lesions, we present a case of congenital LCH with involvement of skin and lung, which was effectively treated with chemotherapy without recurrence for 3 years during the observational period.

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