Publications by authors named "Romana Cuffolo"
Article Synopsis
- The risk of urinary tract infections (UTIs) is highly hereditary, with lifetime susceptibility observed from childhood into adulthood, but there's a lack of comprehensive syntheses of genetic studies.
- This study systematically reviewed genetic polymorphisms linked to UTIs in both children and adults, assessing the strength and reliability of those associations.
- The analysis included 22 studies, finding notable associations with specific genetic variations (CXCR1, IL8, TGF, TLR4, and VDR) particularly in pediatric UTIs, and confirming CXCR1's link with adult UTIs as well.
Introduction And Hypothesis: This manuscript is the International Urogynecology Consultation (IUC) on pelvic organ prolapse (POP) chapter one, committee three, on the Pathophysiology of Pelvic Organ Prolapse assessing genetics, pregnancy, labor and delivery, age and menopause and animal models.
Materials And Methods: An international group of urogynecologists and basic scientists performed comprehensive literature searches using pre-specified terms in selected biomedical databases to summarize the current knowledge on the pathophysiology of the development of POP, exploring specifically factors including (1) genetics, (2) pregnancy, labor and delivery, (3) age and menopause and (4) non-genetic animal models. This manuscript represents the summary of three systematic reviews with meta-analyses and one narrative review, to which a basic scientific comment on the current understanding of pathophysiologic mechanisms was added.
Introduction And Hypothesis: Family and twin studies demonstrate that pelvic organ prolapse (POP) is heritable, but the genetic etiology is poorly understood. This review aimed to identify genetic loci and specific polymorphisms associated with POP, while assessing the strength, consistency, and risk of bias among reported associations.
Methods: Updating an earlier systematic review, PubMed and HuGE Navigator as well as relevant conference abstracts were searched using genetic and phenotype keywords from 2015 to 2020.
Objective: To evaluate the value of fetal scalp blood sampling (FBS) as an adjunct test to cardiotocography, to predict adverse neonatal outcomes.
Study Design: A multicentre service evaluation observational study in forty-four maternity units in the UK. We collected data retrospectively on pregnant women with singleton pregnancy who received FBS in labour using a standardised data collection tool.
Management of unstable and non-longitudinal lie at term in contemporary obstetric practice.
Eur J Obstet Gynecol Reprod Biol
February 2018