Publications by authors named "Romana Butova"
Biomedicines
November 2021
Article Synopsis
- Long non-coding RNAs (lncRNAs) are RNAs longer than 200 nucleotides that have been linked to cancer development through advanced genomic techniques.
- The study aimed to explore the role of lncRNAs in the progression from multiple myeloma (MM) to plasma cell leukemia (PCL) due to a lack of information in this area.
- Researchers identified 13 lncRNAs that were significantly altered in patients, with two specific lncRNAs, LY86-AS1 and VIM-AS1, showing potential as new biomarkers for monitoring the progression of MM to PCL.
Noncoding RNA
January 2019
Article Synopsis
- - Multiple myeloma (MM) is the second most common blood cancer caused by malignant plasma cells in the bone marrow, and although treatments have improved patient survival, the disease's underlying causes remain unclear.
- - Recent research highlights the significance of long non-coding RNAs (lncRNAs) in the progression of various tumors, with over 15,000 lncRNA molecules identified in the human genome exhibiting diverse functions.
- - The review focuses on the role of non-coding RNAs, particularly lncRNAs, in the pathogenesis of MM, suggesting that lncRNAs could be potential biomarkers for the disease.
