Publications by authors named "Romain Lecuyer"
Article Synopsis
- Pneumocystis jirovecii pneumonia (PcP) has high mortality rates, and the effect of immunocompromising diseases on its severity and outcomes hasn't been thoroughly studied.
- This retrospective study analyzed 481 patients diagnosed with PcP between 2011 and 2021, revealing that those with immune-mediated inflammatory diseases (IMIDs) or solid tumors had worse survival rates at 90 days.
- Key factors increasing 90-day mortality included having solid tumors, long-term corticosteroid use, sputum cysts, and higher SOFA scores, with prior corticosteroid therapy, particularly daily prednisone doses ≥10mg, being most impactful among HIV-negative patients.
Background: The role of respiratory coinfections at diagnosis of Pneumocystis jirovecii pneumonia (PcP) on clinical impact has been underestimated.
Methods: A retrospective observational study was conducted January 2011 to April 2019 to evaluate respiratory coinfections at diagnosis of PcP patients in 2 tertiary care hospitals. Coinfection was defined by identification of pathogens from P.
We report the first case of an unexpected exogenous endophthalmitis in a previously healthy woman after a cow's tail's sweep, successfully treated with surgery and linezolid. It is the first case carried out with linezolid to treat endophthalmitis. Therefore, it may challenge the requirement for intravenous antibiotics for long-term treatment.
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