Detection of colonic inflammation with Fourier transform infrared spectroscopy using a flexible silver halide fiber.

Persistent colonic inflammation increases risk for cancer, but mucosal appearance on conventional endoscopy correlates poorly with histology. Here we demonstrate the use of a flexible silver halide fiber to collect mid-infrared absorption spectra and an interval model to distinguish colitis from normal mucosa in dextran sulfate sodium treated mice. The spectral regime between 950 and 1800 cm(-1) was collected from excised colonic specimens and compared with histology.

Use of an endoscope-compatible probe to detect colonic dysplasia with Fourier transform infrared spectroscopy.

Fourier transform infrared (FTIR) spectroscopy is sensitive to the molecular composition of tissue and has the potential to identify premalignant tissue (dysplasia) as an adjunct to endoscopy. We demonstrate collection of mid-infrared absorption spectra with a silver halide (AgCl(0.4)Br(0.

Temporal matching in endoscopic images for remote-controlled robotic surgery.

Temporal matching is applied in the frame of the formation of high-level entities in remote-controlled robotic surgery. The objective is to track tumor boundaries over time to improve the segmentation stage in each image of the sequence to facilitate the tracking and localization of the tumor. It makes use of an attributed string matching technique to find the correspondence between tumor boundaries over time.