Laser-supported partial laparoscopic nephrectomy for renal cell carcinoma without ischaemia time.

Background: To date, elective nephron-sparing surgery is an established method for the exstirpation of renal tumors. While open partial nephrectomy remains the reference standard of the management of renal masses, laparoscopic partial nephrectomy (LPN) continues to evolve. Conventional techniques include clamping the renal vessels risking ischaemic damage of the clamped organ.

Dynamic assessment of angiogenesis in renal cell carcinoma spheroids by intravital microscopy.

Purpose: Renal cell cancer represents a suitable tumor model for in vivo observation of neo-angiogenesis. We used intravital microscopy and the well established dorsal skin fold chamber model to characterize neo-angiogenesis in freely implanted renal cell cancer spheroids.

Material And Methods: Tumor spheroids were implanted into dorsal skin fold chambers of 8 nude mice.