Parallel artificial liquid membrane extraction of acidic drugs from human plasma.

The new sample preparation concept "Parallel artificial liquid membrane extraction (PALME)" was evaluated for extraction of the acidic drugs ketoprofen, fenoprofen, diclofenac, flurbiprofen, ibuprofen, and gemfibrozil from human plasma samples. Plasma samples (250 μL) were loaded into individual wells in a 96-well donor plate and diluted with HCl to protonate the acidic drugs. The acidic drugs were extracted as protonated species from the individual plasma samples, through corresponding artificial liquid membranes each comprising 2 μL of dihexyl ether, and into corresponding acceptor solutions each comprising 50 μL of 25 mM ammonia solution (pH 10).

Stir fabric phase sorptive extraction for the determination of triazine herbicides in environmental waters by liquid chromatography.

Stir fabric phase sorptive extraction (SFPSE), which integrates sol-gel hybrid organic-inorganic coated fabric phase sorptive extraction media with a magnetic stirring mechanism, is presented for the first time. Two flexible fabric substrates, cellulose and polyester were used as the host matrix for three different sorbents e.g.

Stir-membrane solid-liquid-liquid microextraction for the determination of parabens in human breast milk samples by ultra high performance liquid chromatography-tandem mass spectrometry.

In this article, stir-membrane solid-liquid-liquid microextraction (SM-SLLME) is tailored for the analysis of solid matrices and it has been evaluated for the determination of parabens in l breast milk samples. A three-phase microextraction mode was used for the extraction of the target compounds taking advantage of their acid-base properties. The unit allows the simultaneous extraction of the target compounds from the solid sample to an organic media and the subsequent transference of the analytes to an aqueous acceptor phase.

Stir octadecyl-modified borosilicate disk for the liquid phase microextraction of triazine herbicides from environmental waters.

In the present article, a novel extraction/stirring approach in the liquid phase microextraction context is presented. The new technique is based on octadecyl coated borosilicate disks which act as support of the organic extracting solvent thanks to hydrophobic interactions. The disk is integrated in a stirring element which favors the transference of the analytes to the extraction phase.

Stir-membrane liquid microextraction for the determination of paracetamol in human saliva samples.

Background: In this article, stir-membrane liquid microextraction is adapted for the analysis of volume-limited biological samples, using as a model analytical problem the determination of paracetamol in human saliva by LC with UV. A three-phase microextraction mode is used for the extraction of the target analyte, taking advantage of its acid-base properties.

Results: All the variables involved in the extraction have been studied and optimized in depth.

Stir frit microextraction: an approach for the determination of volatile compounds in water by headspace-gas chromatography/mass spectrometry.

In this article, a novel extraction approach, called stir frit microextraction (SFME), is presented. The new approach combines the extractive capability of a commercial polyethylene frit (20 μm of pore size) with the stirring in the same device. The proposed extraction procedure allows the determination of benzene, toluene, ethylbenzene, xylene isomers and styrene (BTEX-S) in water samples.