Structural equation modeling of sleep apnea, inflammation, and metabolic dysfunction in children.

Obstructive sleep apnea (OSA), often concomitant with obesity, increases the risk for the metabolic syndrome. One mechanism that may participate in this association is upregulation of inflammatory pathways. We used structural equation modeling to assess the interrelations between childhood obesity, OSA, inflammation, and metabolic dysfunction.

Follow-up on metabolic markers in children treated for obstructive sleep apnea.

Rationale: In adults, obstructive sleep apnea (OSA) is associated with metabolic dysfunction that improves with treatment of OSA. No equivalent studies exist in children.

Objective: To examine the relationship between metabolic markers and OSA with time and treatment in children.

Metabolic correlates with obstructive sleep apnea in obese subjects.

Objective: To examine links between obstructive sleep apnea (OSA), insulin resistance, and dyslipidemia.

Study Design: Obese (body mass index [BMI] >95th percentile for age and gender) children who snored (n = 62, 46 males, age 10.89 [5-16 years] underwent polysomnography and metabolic studies.