Programmed hierarchical radial association of anisotropic foldamer assemblies.

Herein, we report the first example of a programmed radial assembly of anisotropic microparticles derived from a helical foldamer with a -terminal cysteine residue. Surface-exposed thiols played a crucial role in facilitating the interparticle hydrogen bonding to form higher-order structures in an aqueous solution.

A Hollow Foldecture with Truncated Trigonal Bipyramid Shape from the Self-Assembly of an 11-Helical Foldamer.

The creation of self-assembling microscale architectures that possess new and useful physical properties remains a significant challenge. Herein we report that an 11-helical foldamer self-assembles in a controlled manner to form a series of 3D foldectures with unusual three-fold symmetrical shapes that are distinct from those generated from 12-helical foldamers. The foldamer packing motif was revealed by powder X-ray diffraction technique, and provides an important link between the molecular-level symmetry and the microscale morphologies.