Trichodysplasia spinulosa is a rare dermatological condition caused by a virus that predominantly affects immunosuppressed individuals. In this patient population, including organ transplant recipients, it is essential to maintain a high index of suspicion for possible infectious causes of persistent dermatologic conditions. Early diagnosis can facilitate treatment and help avoid disease progression and complications.
View Article and Find Full Text PDFAlpha-1 antitrypsin (A1AT) is a common genetic disease caused by a mutation in the SERPINA1 gene, predisposing patients to severe premature lung and liver disease. Higher expression of SERPINA1 has been associated with a poor prognosis in patients with high-grade glioblastoma. We present a woman in her 70s with a history of A1AT deficiency treated with weekly plasma-purified A1AT infusions, who presented with metabolic encephalopathy.
View Article and Find Full Text PDFTranscatheter aortic valve replacement (TAVR) has evolved to become a standard management modality for high-risk, moderate, and even low-risk patients with symptomatic aortic stenosis. Infective endocarditis (IE) after a TAVR is rare and difficult to diagnose. Typical sonographic characteristics observed with an echocardiogram in native valve endocarditis may not be present in TAVR-IE cases.
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