Publications by authors named "Rojas Jorge"

Importance: The Veterans Health Administration (VHA) launched the Clinical Resource Hub (CRH), a national telehealth contingency staffing program, to address primary care staffing shortages and improve veteran access to primary care. How this large-scale telehealth intervention affects quality of care is unknown.

Objective: To assess the quality of care for chronic disease management among US veterans receiving high vs low levels of CRH-delivered primary care services and whether racial and ethnic minority veterans experience outcomes similar to those of White veterans when receiving CRH-delivered care.

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Background: Home telehealth (HT) services have rapidly expanded in the Veterans Health Administration (VHA), but little is known about the real-world impact of the expansion of these services on utilization.

Objective: To evaluate the impact of expanding HT diabetes services in VHA on high-cost utilization.

Design: This cohort study used cross-temporal propensity score matching to identify patients with diabetes who would receive HT services (treatment group) with program expansion (treatment group) with a comparison group of patients with diabetes who did not receive HT services (control group) between 2010 and 2018.

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  • - The study analyzed the use of infliximab (IFX) and its biosimilars (IFX-dyyb and IFX-abda) among Veterans with Inflammatory Bowel Disease (IBD), focusing on a group of 1763 IFX-naïve patients over a 365-day period after starting treatment.
  • - Patients were monitored for IFX utilization patterns, dosing, adherence, and persistence, with results indicating differences in these measures across the three treatment groups.
  • - Key findings showed variation in the proportion of days covered and persistence rates, with IFX-RP, IFX-dyyb, and IFX-abda having coverage rates of 66%, 60%, and 69%
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Objective: To evaluate whether the Preventive Health Inventory (PHI)-a virtual care management intervention addressing hypertension and diabetes management implemented nationally in the Veterans Health Administration (VHA)-was delivered equitably among racial/ethnic groups and if existing inequities in hypertension and diabetes outcomes changed following PHI receipt.

Data Sources And Study Setting: We used data from the VHA Corporate Data Warehouse among Veterans enrolled in primary care nationally from February 28, 2021 to March 31, 2022.

Study Design: We used logistic regression to evaluate PHI receipt and hypertension and diabetes outcomes after PHI implementation among Veterans with hypertension and/or diabetes.

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  • High driving pressure (DP) during mechanical ventilation can negatively impact outcomes in pediatric patients with acute respiratory distress syndrome (PARDS), particularly regarding 28-day mortality rates.
  • A study of 184 intubated children showed that those with a DP greater than 15 cm H2O at 72 hours had a higher risk for mortality and longer ventilation duration.
  • Key findings included that lower tidal volumes were linked to decreased mortality risk, while higher plateau pressures in non-survivors highlighted the importance of managing ventilation parameters effectively.*
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Background: The Veterans Health Administration increased synchronous telemedicine (video and telephone visits) in primary care in response to the COVID-19 pandemic.

Objective: Our objective was to determine veteran use patterns of in-person and telemedicine primary care when all modalities were available.

Design: A retrospective cohort analysis.

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Reverse shoulder arthroplasty (RSA) has become a highly successful treatment option for various shoulder conditions, leading to a significant increase in its utilization since its approval in 2003. However, postoperative complications, including scapular notching, prosthetic instability, and component loosening, remain a concern. These complications can often be attributed to technical errors during component implantation, emphasizing the importance of proper preoperative planning and accurate positioning of prosthetic components.

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  • A research team developed a tool that uses natural language processing (NLP) to find important lung health measurements from patient notes in electronic health records for those with a specific lung disease.
  • They looked at notes for over 7,000 patients to compare the numbers found by the NLP tool with results from lung tests.
  • The NLP tool was really good at finding these measurements, capturing three times more accurate values than the traditional testing methods, which can help doctors study and understand the disease better.
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  • The study aimed to compare two outreach strategies for breast cancer screening among female veterans: an automatic referral (opt-out) vs. an automated call with an option to decline (opt-in).
  • The trial involved 883 eligible female veterans over a period from April 2022 to January 2023, measuring outcomes like completed mammograms and scheduled appointments 100 days post-outreach.
  • Results showed no significant difference in completed mammograms between the two groups, although the opt-out group had more canceled referrals, indicating both methods were about equally effective.
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Objective: In the Steroid EliMination In Rheumatoid Arthritis (SEMIRA) trial, 65% of patients with rheumatoid arthritis (RA) in low disease activity (LDA) on stable biologic therapy successfully tapered glucocorticoids. We aimed to evaluate real-world rates of glucocorticoid tapering among similar patients in the Veterans Affairs Rheumatoid Arthritis registry.

Methods: Within a multicenter, prospective RA cohort, we used registry data and linked pharmacy claims from 2003 to 2021 to identify chronic prednisone users achieving LDA after initiating a new biologic or targeted synthetic disease-modifying antirheumatic drug (b/tsDMARD).

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Importance: The COVID-19 pandemic caused significant disruptions in primary care delivery. The Veterans Health Administration (VHA) launched the Preventive Health Inventory (PHI) program-a multicomponent care management intervention, including a clinical dashboard and templated electronic health record note-to support primary care in delivering chronic disease care and preventive care that had been delayed by the pandemic.

Objectives: To describe patient, clinician, and clinic correlates of PHI use in primary care clinics and to examine associations between PHI adoption and clinical quality measures.

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Objectives: Algorithms have been developed to identify rheumatoid arthritis-interstitial lung disease (RA-ILD) in administrative data with positive predictive values (PPVs) between 70 and 80%. We hypothesized that including ILD-related terms identified within chest computed tomography (CT) reports through text mining would improve the PPV of these algorithms in this cross-sectional study.

Methods: We identified a derivation cohort of possible RA-ILD cases (n = 114) using electronic health record data from a large academic medical center and performed medical record review to validate diagnoses (reference standard).

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Risk perceptions of coronavirus disease 2019 (COVID-19) are considered important as they impact community health behaviors. The aim of this study was to determine the perceived risk of infection and death due to COVID-19 and to assess the factors associated with such risk perceptions among community members in low- and middle-income countries (LMICs) in Africa, Asia, and South America. An online cross-sectional study was conducted in 10 LMICs in Africa, Asia, and South America from February to May 2021.

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Aim: Laparoscopic Roux-en-Y gastric bypass (LGB) is the recommended procedure for morbidly obese patients with gastroesophageal reflux disease (GERD). However, there have been reported gastroesophageal reflux symptoms or esophagitis after LGB. Few functional esophageal studies have been reported to date.

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Giant paraesophageal hernias (GPHH) occur frequently in the elderly and account for about 5-10% of all hiatal hernias. Up to now controversy persists between expected medical treatment and surgical treatment. To assess if an indication for surgical repair of GPHH is possible in elderly patients.

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The study of milk fat composition is a priority topic at the international level; however, there are few studies on the composition of triacylglycerides (TAG) and sterols in cow’s milk produced in organic production systems. The objective of this study was to determine the profile of TAG, cholesterol, and other sterols in the fat of raw cow’s milk produced under organic conditions in the municipality of Tecpatán, Chiapas. Every month for one year, milk samples were obtained from three production units (PU 1, 2 and 3) and from the collecting tank (CT) of the municipality (12 months × 4 = 48 samples), in accordance with Mexican regulations.

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Severe viral infections may result in severe illnesses capable of causing acute respiratory failure that could progress rapidly to acute respiratory distress syndrome (ARDS), related to worse outcomes, especially in individuals with a higher risk of infection, including the elderly and those with comorbidities such as asthma, diabetes mellitus and chronic respiratory or cardiovascular disease. In addition, in cases of severe viral pneumonia, co-infection with bacteria such as and is related to worse outcomes. Respiratory viruses like influenza, rhinovirus, parainfluenza, adenovirus, metapneumovirus, respiratory syncytial virus, and coronavirus have increasingly been detected.

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Vaccine hesitancy is considered one of the greatest threats to the ongoing coronavirus disease 2019 (COVID-19) vaccination programs. Lack of trust in vaccine benefits, along with concerns about side effects of the newly developed COVID-19 vaccine, might significantly contribute to COVID-19 vaccine hesitancy. The objective of this study was to determine the level of vaccine hesitancy among communities in particular their belief in vaccination benefits and perceived risks of new vaccines.

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Vaccine hesitancy, defined as the reluctance or rejection in receiving a vaccine despite its availability, represents a major challenge to global health efforts aiming to control the ongoing COVID-19 pandemic. Understanding the possible factors correlated with COVID-19 vaccine hesitancy using a refined well-informed approach can be helpful to address the phenomenon. The current study aimed to evaluate COVID-19 vaccine acceptance rates using four hypothetical scenarios of varying levels of vaccine efficacy and safety profiles in ten Asian, African and South American countries.

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Background: The clinical presentation and severity of Multisystem Inflammatory Syndrome in Children associated with COVID-19 (MIS-C) is widespread and presents a very low mortality rate in high-income countries. This research describes the clinical characteristics of MIS-C in critically ill children in middle-income countries and the factors associated with the rate of mortality and patients with critical outcomes.

Methods: An observational cohort study was conducted in 14 pediatric intensive care units (PICUs) in Colombia between April 01, 2020, and January 31, 2021.

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  • Juvenile idiopathic arthritis (JIA) is the most common rheumatological condition in children, and treatment with tumor necrosis factor inhibitors (TNFi) is effective but can increase infection risk, making vaccinations essential.
  • This study evaluated how well JIA patients treated with monoclonal antibodies respond to the pneumococcal vaccine, using data from a clinical setting in Santiago, Chile.
  • Results showed that most patients achieved protective antibody levels after vaccination, with factors like vaccination timing and lymphocyte count potentially affecting their immune response.
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Introduction: Severe combined immunodeficiency (SCID) is the most severe form of primary immunodeficiency. To date, there is little local information about this disease.

Objective: To describe the epidemiology, complications, prognosis, and use of the BCG vaccine in Chilean patients with SCID.

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  • - The review investigated the effectiveness of tranexamic acid in reducing adverse outcomes such as transfusions, infections, and hematomas for patients undergoing shoulder arthroplasty.
  • - After analyzing data from four randomized controlled trials with 375 patients, the meta-analysis found no significant impact of tranexamic acid on transfusion rates and concluded that current evidence is insufficient to measure its effects on infection and hematoma formation.
  • - Despite its known benefits in reducing blood loss, the study emphasizes that there is no conclusive evidence supporting the use of tranexamic acid for improving transfusion, infection, or hematoma outcomes in shoulder arthroplasty procedures.
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  • Therapeutic Level IV indicates a category of evidence used in clinical research which typically includes case series or poor-quality cohort studies.
  • This level is important for assessing the effectiveness of treatments when higher levels of evidence are not available.
  • The "Instructions for Authors" section provides detailed guidelines on how to properly classify and report different levels of evidence in scholarly articles.
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