Structural and Functional Analysis of Groundnut bud necrosis virus (GBNV) Using Computational and Biochemical Approaches.

Groundnut bud necrosis virus (GBNV) belonging to the genus Orthotospovirus is transmitted by its vector Thrips palmi. It is a tri-segmented RNA virus that consists of L, M, and S RNA segments. We analysed the secondary structure features of GBNV proteins through various software and predicted the transmembrane helix, glycosylation, and signal peptidase sites within the GBNV protein sequences (G, G, N, NSm, and NSs).

Polyubiquitin protein of Aedes aegypti as an interacting partner of dengue virus envelope protein.

Dengue virus (DENV) is an arbovirus that comprises four antigenically different serotypes. Aedes aegypti (Diptera: Culicidae) acts as the principal vector for DENV transmission, and vector control is crucial for dengue fever epidemic management. To design effective vector control strategies, a comprehensive understanding of the insect vector and virus interaction is required.

Understanding the role of insects in the acquisition and transmission of antibiotic resistance.

Antibiotic resistance (AR) is a global healthcare threat that requires a comprehensive assessment. Poorly regulated antibiotic stewardship in clinical and non-clinical settings has led to a horizontal dissemination of AR. A variety of often neglected elements facilitate the circulation of AR from antibiotic sinks like concentrated animal feeding operations and healthcare settings to other environments that include healthy human communities.

Detection of unprecedented level of antibiotic resistance and identification of antibiotic resistance factors, including QRDR mutations in Escherichia coli isolated from commercial chickens from North India.

Aim: This study aimed to investigate the occurrence of antibiotic resistance phenotype and simultaneously understand its genetic basis in Escherichia coli isolated from the cloacal swabs of commercial chickens from north India.

Methods And Results: Escherichia coli isolates were assessed for susceptibility to 14 different antibiotics using the disc-diffusion technique and were screened for the presence of 22 antibiotic resistance genes (ARGs) by employing PCR. Isolates were found to be highly resistant to fluoroquinolones (nalidixic acid 91%, norfloxacin 73% and ciprofloxacin 66%), tetracycline (71%), beta-lactams (ampicillin 49% and amoxicillin/clavulanic acid 37%), co-trimoxazole (48%), streptomycin (31%) and chloramphenicol (28%); and comparatively less resistant to cefazolin (13%), amikacin (10%), aztreonam (4%), gentamicin (4%) and ceftriaxone (3%).

Implication of the Whitefly, , Collagen Protein in Begomoviruses Acquisition and Transmission.

Begomoviruses are the largest group of plant viruses transmitted exclusively by the whitefly, (Gennadius), in a persistent, circulative, and nonpropagative manner. Begomoviruses in association with cause enormous loss to world agricultural crops. Transmission, retention, and circulation of begomovirus in are facilitated by its interaction with several proteins of the insect and its endosymbionts.

Comparison of sagittal anchorage conservation of mini-implants and modified Nance palatal buttons.

Objective: To compare the anchorage potential of mini-implants with modified Nance palatal buttons during simultaneous first and second maxillary molar distalization.

Methods: Mini-implants (1.4 x 10 mm) placed to obtain indirect anchorage for maxillary molar distalization using a superelastic Ni-Ti open coil spring were compared with anchorage derived from a modified Nance palatal button incorporated in a distal jet appliance.

Distalization of molars using two stage mini-implants -- a case report.

This article describes a two stage mini-implant approach to distalize the maxillary molars and then retract the anterior teeth into class I, providing a non-compliant, non-extraction treatment.

Late-developing supernumerary mandibular premolar: a case report.

This report presents a case of a patient who developed a supernumerary mandibular premolar during the course of orthodontic treatment. Evidence of this tooth comes from consecutive panoramic radiographs. It is not routine practice to screen for developing supernumerary teeth during orthodontic treatment.