Publications by authors named "Rohini Sodhi"
J Enzyme Inhib Med Chem
December 2018
Article Synopsis
- A new one-pot method has been developed to synthesize various (1,3,4-oxadiazol-2-yl)anilines using isatins and hydrazides, with molecular iodine as the catalyst.
- This efficient process involves multiple steps, including condensation and ring cleavage, ultimately leading to the formation of a C-O bond in a single reaction.
- The synthesized compounds were tested for their ability to inhibit carbonic anhydrase enzymes, showing promising activity, especially some that are highly selective for the hCA II isoform.
