Guided waves (GW) allow fast inspection of a large area and hence have received great interest from the structural health monitoring (SHM) community. Fiber Bragg grating (FBG) sensors offer several advantages but their use has been limited for the GW sensing due to its limited sensitivity. FBG sensors in the edge-filtering configuration have overcome this issue with sensitivity and there is a renewed interest in their use.
View Article and Find Full Text PDFPurpose: The common marmoset (Callithrix jacchus) provides an ideal model to study early development of primates, and an in vivo platform to validate conclusions from in vitro studies of human embryos and embryo models. Currently, however, no established staging atlas of marmoset embryonic development exists. Using high-resolution, longitudinal ultrasound scans on live pregnant marmosets, we present the first dynamic in vivo imaging of entire primate gestation beginning with attachment until the last day before birth.
View Article and Find Full Text PDFThe fat mass and obesity-associated gene () codes for a DNA/RNA demethylase. Pathological variants in this gene are rare, with only three reports in the literature, all with mutations in the catalytic domain. We report the first biallelic human variant in fat mass and obesity-associated gene (c.
View Article and Find Full Text PDFThe controlled interaction of work material and cutting tool is responsible for the precise outcome of machining activity. Any deviation in cutting parameters such as speed, feed, and depth of cut causes a disturbance to the machining. This leads to the deterioration of a cutting edge and unfinished work material.
View Article and Find Full Text PDFStructural health monitoring (SHM) systems may allow a reduction in maintenance costs and extend the lifetime of the structure. As a result, they are of interest to the research community. Ideally, the SHM methods should be low cost, while being able to detect and localize small levels of damage reliably and accurately.
View Article and Find Full Text PDFRecent advancements in fiber optic methods have enabled their use for guided wave sensing. It opens up new possibilities for Structural Health Monitoring. The aim of this paper is to provide insight for the physics related to guided wave propagation and coupling between the optical fiber and solid structure.
View Article and Find Full Text PDFSensors (Basel)
November 2021
Guided waves (GW) and acoustic emission (AE) -based structural health monitoring (SHM) have widespread applications in structures, as the monitoring of an entire structure is possible with a limited number of sensors. Optical fiber-based sensors offer several advantages, such as their low weight, small size, ability to be embedded, and immunity to electro-magnetic interference. Therefore, they have long been regarded as an ideal sensing solution for SHM.
View Article and Find Full Text PDFStructural Health Monitoring (SHM) systems have a potential to reduce lifecycle costs of structures. As a result, there is a lot of active research in the area for SHM of civil and mechanical structures. Guided waves (GW) based SHM techniques allow monitoring of large plate-like structures with a few sensors and have been identified as the most promising of techniques for SHM.
View Article and Find Full Text PDFChromosomal instability leading to aneuploidy is pervasive in early human embryos and is considered as a major cause of infertility and pregnancy wastage. Here we provide several lines of evidence that blastocysts containing aneuploid cells are worthy of in vitro fertilization transfer. First, we show clinically that aneuploid embryos can lead to healthy births, suggesting the presence of an in vivo mechanism to eliminate aneuploidy.
View Article and Find Full Text PDFStructural health monitoring (SHM) systems help in reducing maintenance cost and avoiding catastrophic failure of the structure. As a result, they have been a focus of research for the past few decades. Ideally, the methods employed should be low cost and able to detect and localize small levels of damage reliably and accurately.
View Article and Find Full Text PDFThere is continuing research in the area of structural health monitoring (SHM) as it may allow a reduction in maintenance costs as well as lifetime extension. The search for a low-cost health monitoring system that is able to detect small levels of damage is still on-going. The present study is one more step in this direction.
View Article and Find Full Text PDFGuided waves (GW) allow fast inspection of a large area and hence have attracted research interest from the structural health monitoring (SHM) community. Thus, GW-based SHM is ideal for thin structures such as plates, pipes, etc., and is finding applications in several fields like aerospace, automotive, wind energy, etc.
View Article and Find Full Text PDFSensors (Basel)
December 2018
The paper presents a proof of concept of a new methodology for the load estimation in beam-like structures under complex loading. The paper customizes a Kalman Filter (KF) based estimation technique which is shown to be robust to the presence of measurement noise as well as the changing condition of the beam for estimation of loads in beam-like structures. The methodology was validated using numerical as well as experimental data.
View Article and Find Full Text PDFObjective: The purpose of this study was to review screening mammograms obtained in one practice with the primary endpoint of determining the rate of detection of breast cancer and associated prognostic features in women 40-44 and 45-49 years old.
Materials And Methods: The retrospective cohort study included women in their 40s with breast cancer detected at screening from June 2014 through May 2016. The focus was on cancer detection rate, pathologic findings, and risk factors.
The dynamics of dissolved oxygen (DO) and shear stress in the vasculature microenvironment play a major role in determining the fate of stem cells in adults and during early embryonic development. In this study, we present a microbioreactor (MBR) that provides independent control over oxygen tension and shear stress in cultures of stem and progenitor cell types. We first describe the design principles and use a model-driven approach for the optimization of the MBR geometry and operating conditions prior to its fabrication and assembly.
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