Meatal stenosis and lichen sclerosus in children: is it a real risk? A single-centre retrospective observational study.

Background: Early diagnosis, early treatment and long-term follow-up in paediatric patients with Lichen Sclerosus (LS) are mandatory to avoid complications such as urethral meatal stenosis.

Methods: All patients older than five years who underwent circumcision from January 2015 to December 2021 at our centre with positive histology for LS were included. Demographic, preoperative, surgical and postoperative data were analysed.

Thousands of Years of Pastoralism Don't Count: Coprophagous Beetles Prefer Exotic Alpaca Dung to That of Cattle.

Dung beetles mostly feed on mammal dung. Throughout the European Alps, the dung produced by local domestic ungulates attracts many species of dung beetles, giving rise to rich and diversified communities that play an important role in the Alpine agricultural ecosystem. There is, therefore, understandable concern about the introduction of exotic livestock, such as alpacas ( (Linnaeus, 1758)), into the region.

Pony feeding management: the role of morphology and hay feeding methods on intake rate, ingestive behaviors and mouth shaping.

In the last decade, haynets and slow feeders have been promoted as sustainable tools to improve the feeding management of horses and reduce forage waste, but little is known about their effects on ponies. Therefore, the aim of this study was to analyze the effects of different hay feeding methods on the ingestive behaviors, intake rate and mouth shaping of ponies belonging to two breed types, which are characterized by different head morphologies. Shetland type (SH,  = 5) and Welsh/Cob type (WC,  = 4) ponies were fed hay using four feeding methods: on the ground (G), a fully filled haynet (HF), a partially filled haynet (HL), and a slow-feeder hay box (HB).

Sternal cleft and pectus excavatum: an overlooked congenital association?

Background: Sternal cleft (SC), a rare thoracic malformation, is associated with pectus excavatum (PE) in 2.6-5% of cases. It remains unclear if these conditions are congenitally linked or if SC repair triggers PE.

Color polymorphism and mating trends in a population of the alpine leaf beetle Oreina gloriosa.

The bright colors of Alpine leaf beetles (Coleoptera, Chrysomelidae) are thought to act as aposematic signals against predation. Within the European Alps, at least six species display a basal color of either blue or green, likely configuring a classic case of müllerian mimicry. In this context, intra-population color polymorphism is paradoxical as the existence of numerous color morphs might hamper the establishment of a search image in visual predators.

Navigating the complexities of encephalocraniocutaneous lipomatosis: a case series and review.

Introduction: Encephalocraniocutaneous lipomatosis (ECCL) is a rare congenital syndrome with complex skin, eye, and central nervous system (CNS) symptoms. Diagnosis and treatment are challenging due to its rarity and diverse manifestations. It often involves issues like porencephalic cysts, cortical atrophy, and low-grade gliomas in the CNS, resulting in developmental delays.

Dung removal increases under higher dung beetle functional diversity regardless of grazing intensification.

Dung removal by macrofauna such as dung beetles is an important process for nutrient cycling in pasturelands. Intensification of farming practices generally reduces species and functional diversity of terrestrial invertebrates, which may negatively affect ecosystem services. Here, we investigate the effects of cattle-grazing intensification on dung removal by dung beetles in field experiments replicated in 38 pastures around the world.

A case report of hemorrhagic presentation of diffuse neonatal hemangiomatosis (DNH) associated to obstructive hydrocephalus: Medical and neurosurgical considerations.

Background: Diffuse neonatal hemangiomatosis (DNH) is a rare disorder typically recognized at birth or during the neonatal period. DNH involves three or more organ systems, including the central nervous system (CNS). In these cases, serious complications such as hemorrhages and obstructive hydrocephalus can develop.

Spatio-temporal modelling suggests that some dung beetle species (Coleoptera: Geotrupidae) may respond to global warming by boosting dung removal.

In the current framework of changes to the global climate, information on the thermal tolerance of dung beetles is crucial to understand how they might cope with increases in land temperature in terms of survival and ecosystem service provision. In this spatio-temporal modelling study, we investigated the thermal tolerance and effect of temperature changes on dung removal by three dung beetle species (Coleoptera: Geotrupidae) living within the 600-1400 m altitudinal belt in the Italian Alps. We chose large tunneler beetles because of their pivotal role in dung removal and nutrient recycling, important ecosystem services for maintaining the viability and profitability of the Alpine pastoral system.

Effect of pony morphology and hay feeding methods on back and neck postures.

The application of hay feeding devices, such as the use of hay nets or slow feeders, can help with the management of weight in ponies; however, there is still a lack of knowledge regarding their effect on equine posture. Therefore, the aim of the study was to assess the effect of different feeding devices on the posture of ponies using morphometric analysis. Two different breed types, Shetland type (SH, n = 5) versus Welsh Cob type (WC, n = 4), were fed the same forage in four different ways: on the ground (G), using a fully filled haynet (HF), using a partially filled haynet (HL) and using a slow-feeder hay box (HB).

Behavioural Repeatability and Behavioural Syndrome in the Dung Beetle (Coleoptera, Scarabaeidae).

Although personality studies have primarily focused on vertebrates, the evidence showing invertebrates to be capable of displaying personalities has been steadily growing in recent years. In this study, we investigated the behavioural repeatability (repetition of a behaviour over time) and behavioural syndromes (a set of correlated behaviours) in , which is a dung beetle species showing complex sub-social behaviour. We analysed three behaviours (activity, thanatosis and distress call emission) by measuring seven distinct behavioural traits (i.

The First Anti-Snakebite and Hepatoprotective Characterization of a Trypsin Kunitz-like Inhibitor (EcTI) from the Plant A Case of Two Soul Mates Meeting.

Snake venom serine protease (SVSP) interferes with the regulation and control of important biological reactions in homeostasis and can be classified as an activator of the fibrinolytic system and platelet aggregation. Our group has recently isolated a new serine protease from total venom (Cdtsp-2). This protein exhibits edematogenic capacity and myotoxic activity.

In Silico Evaluation of Quercetin Methylated Derivatives on the Interaction with Secretory Phospholipases A2 from and .

Quercetin derivatives have already shown their anti-inflammatory potential, inhibiting essential enzymes involved in this process. Among diverse pro-inflammatory toxins from snake venoms, phospholipase A2 is one of the most abundant in some species, such as and from the Viperidae family. These enzymes can induce the inflammatory process through hydrolysis at the sn-2 position of glycerophospholipids.

Theoretical evaluation of the malathion and its chemical derivatives interaction with cytosolic phospholipase A2 from zebrafish.

Cytosolic phospholipase A2 (cPLA2) belongs to a large family of proteins and plays a crucial role in the regulation of arachidonic acid metabolism and inflammation cascade in zebrafish (Danio rerio). This enzyme with a molecular weight of 85 kDa, has two distinct domains. One is the regulatory and calcium-dependent (Ca) domain called C2, the other is the catalytic α/β hydrolase Ca-independent domain, where serine and aspartic acid catalytic dyad residues are present.

Spectral density reconstruction with Chebyshev polynomials.

Accurate calculations of the spectral density in a strongly correlated quantum many-body system are of fundamental importance to study its dynamics in the linear response regime. Typical examples are the calculation of inclusive and semiexclusive scattering cross sections in atomic nuclei and transport properties of nuclear and neutron star matter. Integral transform techniques play an important role in accessing the spectral density in a variety of nuclear systems.

Continuous phenotypic modulation explains male horn allometry in three dung beetle species.

Many dung beetle species show male horn polyphenism, the ability of males to develop into distinct phenotypes without intermediate forms as a response to the larval growth environment. While males with long (majors) and rudimentary (minor) horn have been widely reported in literature, little is known about the existence of individuals with intermediate horn length. Here we investigate the occurrence of intermediates in natural populations of three dung beetle species (Onthophagus furcatus, Copris lunaris and C.

Standard model physics and the digital quantum revolution: thoughts about the interface.

Advances in isolating, controlling and entangling quantum systems are transforming what was once a curious feature of quantum mechanics into a vehicle for disruptive scientific and technological progress. Pursuing the vision articulated by Feynman, a concerted effort across many areas of research and development is introducing prototypical digital quantum devices into the computing ecosystem available to domain scientists. Through interactions with these early quantum devices, the abstract vision of exploring classically-intractable quantum systems is evolving toward becoming a tangible reality.

Integrating thermal tolerance, water balance and morphology: An experimental study on dung beetles.

The impacts of extreme and rising mean temperatures due to climate change can pose significant physiological challenges for insects. An integrated approach that focuses on mechanisms of body temperature regulation, water balance and morphology may help to unravel the functional traits underpinning thermoregulation strategies and the most relevant trade-offs between temperature and water balance regulation. Here, we focused on four species of tunneler dung beetles as important providers of ecosystem services.

Physiological, morphological and ecological traits drive desiccation resistance in north temperate dung beetles.

Background: Increasing temperatures and changes in precipitation patterns threaten the existence of many organisms. It is therefore informative to identify the functional traits that underlie differences in desiccation resistance to understand the response of different species to changes in water availability resulting from climate change. We used adult dung beetles as model species due to their importance to ecosystem services.

Studying the Shape Variations of the Back, the Neck, and the Mandibular Angle of Horses Depending on Specific Feeding Postures Using Geometric Morphometrics.

The effects of specific feeding positions upon the horse's shape variations of the back and neck postures as well as the variations of the mandibular angle have never been objectively studied. For this reason, geometric morphometrics was applied. Six horses, aged 14 ± 8 years (mean ± standard deviation, SD), were video-recorded while using three different feeding positions: on the ground-control position (CP); neck held 15 ± 3° below withers height with low hay net position (LP); neck held 15 ± 3° above withers height with high hay net position (HP).

Exact representations of many-body interactions with restricted-Boltzmann-machine neural networks.

Restricted Boltzmann machines (RBMs) are simple statistical models defined on a bipartite graph which have been successfully used in studying more complicated many-body systems, both classical and quantum. In this work, we exploit the representation power of RBMs to provide an exact decomposition of many-body contact interactions into one-body operators coupled to discrete auxiliary fields. This construction generalizes the well known Hirsch's transform used for the Hubbard model to more complicated theories such as pionless effective field theory in nuclear physics, which we analyze in detail.

Male Horn Lack of Allometry May be Tied to Food Relocation Behaviour in Lifting Dung Beetles (Coleoptera, Scarabaeidae, Eucraniini).

The small dung beetle tribe Eucraniini includes extremely specialized species that have been defined as "lifters" according to their food relocation behaviour. They are characterized by the presence of well-developed expansions on the head and pronotum, which can be included in the large and varied group of horns, whose presence is usually related to complex reproductive tactics. In this study, two closely related species, and , were examined employing traditional and geometric morphometrics to test whether the Eucraniini has polymorphic males that might exhibit different reproductive tactics, as in the sister tribe Phanaeini, for which a male trimorphism was demonstrated.

The Phylogenetic Relationships of n.gen. (Coleoptera, Scarabaeidae, Onthophagini) Evaluated by Phenotypic Characters.

A necro-coprophagous new genus tha is widespread in the whole Sub-Saharan Africa was identified within the tribe Onthophagini and named n.gen. The new genus, which is well characterized by an exclusive set of characters, comprises, at present, 26 species.