A comparison of neural feature extraction methods for brain-machine interfaces.

Brain-machine interfaces (BMIs) have shown promise in augmenting people's control of their surroundings, especially for those suffering from paralysis due to neurological disorders. This paper describes an experiment using the rodent model to explore information available in neural signals recorded from chronically implanted intracortical microelectrode arrays. In offline experiments, a number of neural feature extraction methods were utilized to obtain neural activity vectors (NAVs) describing the activity of the underlying neural population while rats performed a discrimination task.

Patterning poly(organophosphazenes) for selective cell adhesion applications.

Five polyphosphazenes with different hydrophilicites were synthesized and screened in vitro. The purpose was to identify unique types of polymeric substrates that distinctly favored or markedly prevented cellular adhesion. The SK-N-BE(2c) human neuroblastoma cell line, utilized for its electrogenic responses, was used to test this differential adhesion.