Publications by authors named "Roger M L Smith"
Article Synopsis
- The study investigates the unknown causes of sirenomelia by comparing the anatomical defects in two cases of sirenomelia and Potter's sequence, a rare fetal disorder.
- Using advanced imaging technologies and genetic analysis, researchers found both fetuses were male and exhibited overlapping, yet distinct, defects, particularly in the ears, brain, urogenital system, limbs, pelvis, and vertebral column.
- The findings suggest that abnormalities in the axial mesoderm are likely responsible for the observed conditions, with one fetus showing defects similar to severe pelvic outlet syndrome and the other to axial mesodermal dysplasia syndrome.
