Publications by authors named "Roger C Toffle"

Background: An unruptured third trimester rudimentary horn pregnancy is rare, life threatening, and can go undetected until the onset of symptoms. Given the high risk of uterine rupture, conservative management after viability is controversial.

Case: A 21 year-old with a 32-week rudimentary horn pregnancy, diagnosed via exploratory laparotomy five days earlier, presented with acute right upper quadrant pain.

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Dr. Albrink's review of information available in 1969 did not allow her to determine a physiologic basis for the use of hCG or any proof of immediate or long term benefit. Subsequent discoveries and clinical studies only support her impressions.

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Background: An invasive mole is a form of persistent trophoblastic disease. The traditional surgical treatment is hysterectomy.

Case: A young nullipara presented with a positive pregnancy test 6 months following a suction curettage for an incomplete abortion.

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The finding of a serum testosterone level greater than 200 ng/dl in a woman with virilization raises concerns about an androgen producing tumor. This case report demonstrates that chronic annovulation in association with insulin resistance can cause significant elevations in the level of serum testosterone, and describes the therapeutic benefit of insulin sensitizing agents in reversing hyperandrogenemia.

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