Testing the Testers: Are Young Men Who Have Sex With Men Receiving Adequate HIV Testing and Counseling Services?

Background: The United States Centers for Disease Control and Prevention promote HIV testing every 6 months among young men who have sex with men (YMSM) to facilitate entry into the HIV prevention and care continuum. Willingness to be tested may be influenced by testing services' quality. Using a novel mystery shopper methodology, we assessed YMSM's testing experiences in 3 cities and recommend service delivery improvements.

Physical Intimate Partner Violence and Controlling Behavior in Mexican University Students and Their Attitudes Toward Social Limits.

This study explored patterns of controlling behavior, physical violence, and attitudes toward social limits in young Mexican university students in light of the effect that socialization processes have in attitudes toward social norms and violent behavior as indicated in some of the literature. A total of 437 male and female heterosexual participants residing in Ciudad Juárez, Mexico, provided information on their perpetration/victimization experiences of controlling behavior (by means of the Controlling Behaviors Scale) and physical violence (using the Revised Conflict Tactics Scales [CTS2]) and their attitudes toward social limits (using the Attitudes Toward Social Limits scale). Results indicate similar chronicity levels of experienced controlling behavior and physical violence perpetration/victimization between the sexes.

Pathogenesis and immune response in tuberculous meningitis.

Cerebral tuberculosis is the most severe type of extrapulmonary disease that is in developing countries highly predominant in children. Meningeal tuberculosis is the most common form and usually begins with respiratory infection followed by early haematogenous dissemination to extrapulmonary sites involving the brain. In comparison with the lung, Mycobacterium tuberculosis induces a very different immune response when infect the central nervous system.

Pharmacogenetic screening of N-acetyltransferase 2, thiopurine s-methyltransferase, and 5,10-methylene-tetrahydrofolate reductase polymorphisms in Northwestern Mexicans.

Specific information about the population pharmacogenetics can be the starting point to study the inheritance of these traits, to design individual drug therapy, and to develop new drugs rationally. Pharmacogenetic studies have been performed in some regions of Mexico, such as Central and Northeast, but this kind of study has not been conducted in the Northwest region so far. Here, we report the distribution of NAT2, TPMT, and MTHFR gene polymorphisms in Baja California, Mexico.

Mutation in mce operons attenuates Mycobacterium tuberculosis virulence.

On the Mycobacterium tuberculosis genome there are four mce operons, all of which are similar in sequence and organization, and code for putatively exported proteins. To investigate whether Mce proteins are essential for virulence, we generated knock-out mutants in mce1, mce2 and mce3 operons of M. tuberculosis and evaluated their ability to multiply in a mammalian host.