Breast MRI, digital mammography and breast tomosynthesis: comparison of three methods for early detection of breast cancer.

Breast cancer is the most common malignancy in women and early detection is important for its successful treatment. The aim of this study was to investigate the sensitivity and specificity of three methods for early detection of breast cancer: breast magnetic resonance imaging (MRI), digital mammography, and breast tomosynthesis in comparison to histopathology, as well as to investigate the intraindividual variability between these modalities. We included 57 breast lesions, each detected by three diagnostic modalities: digital mammography, breast MRI, and breast tomosynthesis, and subsequently confirmed by histopathology.

Ultrastructural changes in surface topography, glycocalyx and plasma membrane interior of tumor cells during exocytosis of mucus.

Plasma membrane changes, which occur during exocytosis, were studied by electron microscopy in six specimens of primary mucous-producing adenocarcinoma of human urinary bladder. The luminal surfaces of non-secretory neoplastic cells display numerous microvilli, which have a thick ruthenium red-positive glycocalyx. Neoplastic secretory cells have a smooth luminal surface with relatively few microvilli.

Primary adenocarcinomas of the human urinary bladder: histochemical, immunological and ultrastructural studies.

Neoplastic and non-neoplastic tissue specimens from ten patients with primary adenocarcinoma of the urinary bladder were examined. Most of these tumors were associated with either foci of transitional cell carcinoma and/or with glandular metaplasia of the bladder epithelium. The mucin produced by the neoplastic cells was PAS, alcian blue, mucicarmine, PB/KOH/PAS, and RPB/KOH/PAS-positive.

[Pathomorphologic and ultrastructural characteristics of endocardial Cysticercus cellulosae].

A case is presented of a solitary endocardial cysticercus of cellulose discovered at a biopsy in the left auricula of the heart, got by a 36-year old patient at the operation who had a mitral and aortal defect caused by a reumatic endocarditis. The cisticercus is implanted on the surface of an intact endothelium and the fibroelastic structure of the superficial part of the endocardium is preserved. Inflammation of the endocardium and the myocardium is presented by a perivascular infiltrates eosinophile granulocytes, plasms cells and lymphocytes, suggesting an allergic nature of inflammation.