Prognostic role of Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio in critically ill COVID-19 patients: A retrospective study.

Introduction: Critical coronavirus disease (COVID-19) patients have a high mortality rate. To identify high-risk patients, first-level healthcare facilities can use the neutrophil-lymphocyte ratio (NLR) and the plateletlymphocyte ratio (PLR) as prognostic markers. We aimed to assess the NLR and the PLR profile in critically ill COVID-19 patients to predict disease severity.

Green coffee extract modifies body weight, serum lipids and TNF-α in high-fat diet-induced obese rats.

Objective: Currently, there are many efforts to find functional nutrients for obesity management, and the green coffee extract is a potential candidate. This study aimed to examine the effect of low dose administration of  green coffee extract on body weight, serum lipids, and TNF-α level in high-fat diet-induced obese rats.

Results: Administration of green coffee extract to high-fat diet-induced obese male Wistar rats (Rattus norvegicus) reduced body weight, total serum cholesterol, and triglyceride at the dose of 10, 20, and 40 mg/kg BW/day; lowered serum LDL-cholesterol at the treatment dose of 20 mg/kg BW/day (p < 0.