Predictors of clinically significant anhedonia in refractory epilepsy.

Background: Anhedonia, the inability to feel pleasure or motivation for reward, is a core feature of depression in epilepsy, but can occur independent from depression. It is reported in over a third of people with epilepsy and has a significant impact on quality of life.

Objectives: This study determined whether specific features of medication refractory epilepsy are predictive of anhedonia.