Expression levels of specific microRNAs are increased after exercise and are associated with cognitive improvement in Parkinson's disease.

There is a consensus regarding the efficacy of physical exercise in maintaining or improving human health; however, there are few studies examining the effect of physical exercise on the expression levels of microRNAs (miRNA/miRs) in Parkinson's disease (PD). The aim of the present study was to investigate the effects of an interval training program on a cycle ergometer on the expression levels of miR‑106a‑5p, miR‑103a‑3p and miR‑29a‑3p in serum samples from men with PD. This was a quasi‑experimental study with pre‑ and post‑testing and with a non‑equivalent group design.

Effects of Physical Exercise on the Expression of MicroRNAs: A Systematic Review.

Silva, FCd, Iop, RdR, Andrade, A, Costa, VP, Gutierres Filho, PJB, and Silva, Rd. Effects of physical exercise on the expression of microRNAs: A systematic review 34(1): 270-280, 2020-Studies have detected changes in the expression of miRNAs after physical exercise, which brings new insight into the molecular control of adaptation to exercise. Therefore, the objective of the current systematic review of experimental and quasiexperimental studies published in the past 10 years was to assess evidence related to acute effects, chronic effects, and both acute and chronic effects of physical exercise on miRNA expression in humans, as well as its functions, evaluated in serum, plasma, whole blood, saliva, or muscle biopsy.

Effects of physical exercise programs on cognitive function in Parkinson's disease patients: A systematic review of randomized controlled trials of the last 10 years.

Background: Given the relative importance of cognitive impairment, there was considerable interest in identifying the cognitive profile of PD patients, in order to ensure specific and appropriate therapeutic interventions.

Purpose: To determine the effects of physical exercise programs on cognitive function in PD patients, compared with the control group.

Data Sources: Medline, Cochrane, Scopus, PEDro and Web of Science (last searched in September 2016).

microRNAs involved in Parkinson's disease: A systematic review.

The aim of the present study was to determine the expression of blood microRNAs (miRNAs) involved in PD in humans. For this purpose the following electronic databases were selected: MEDLINE by Pubmed, Scopus and Web of Science. The search strategy included the proposed descriptors in the Medical Subject Headings.

Evaluation protocols of hand grip strength in individuals with rheumatoid arthritis: a systematic review.

Hand grip strength is a useful measurement for individuals with rheumatoid arthritis, since this disease is often associated with functional anomalies of the hands and a consequent reduction in muscular strength. Thus, the standardization of the test protocol is important in relation to make reproducible and reliable studies. The aim of this systematic review was to verify the parameters associated with the measurement of the hand grip strength in individuals with rheumatoid arthritis.